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Table 2 Hemodynamic and functional hemodynamic markers in fluid responders and non-responders before (A) and after (B) intra-abdominal hypertension induction

From: Influence of tidal volume on pulse pressure variation and stroke volume variation during experimental intra-abdominal hypertension

A.

 

∆SVI >15 %

P-value

 

ALL (n = 24)

YES (n = 10)

NO (n = 14)

 

CI (l/min/m2)

4.5 (4.0, 5.5)

4.5 (4.1, 5.5)

4.4 (3.9, 5.4)

0.79

∆CI (%)

5.7 (1.1, 15.1)

14.9 (3.7, 24.6)

4.7 (-8.3, 8.2)

0.106

∆SVI (%)

10.9 (2.6, 21.2)

23.2 (18.1, 33.3)

5.0 (-8.1, 9.4)

<0.001

SVI (ml/m2)

36.5 (32, 40)

31 (30, 39)

37 (35, 40)

0.001

SVV (%)

    

VT 6 ml/kg

4 (3, 6)

4 (3.8, 6)

3 (2, 5)

0.12

VT 12 ml/kg

8 (6, 11)

10 (9, 12)

6.5 (4, 8)

0.011

VT 18 ml/kg

9 (6, 12)

12 (9, 16)

6 (5, 9)

0.011

PPV (%)

    

VT 6 ml/kg

4 (3, 6)

5 (3, 7)

3 (2, 4)

0.019

VT 12 ml/kg

7 (5, 11)

11 (8, 19)

6 (5, 7)

<0.001

VT 18 ml/kg

9 (7, 15)

14 (9, 27)

8 (5, 9)

0.001

HR (bpm)

129 (117, 163)

139 (119, 191)

129 (114, 155)

0.045

MAP (mmHg)

69 (63, 80)

67 (63,71)

73 (64, 83)

0.214

CVP (mmHg)

7 (6, 10)

7 (6, 8)

8 (7, 11)

0.016

SVRI

1070 (895,1408)

1144 (880,1189)

1041 (913,1475)

0.837

B.

 

∆SVI > 15 %

P-value

 

ALL (n = 12)

YES (n = 4)

NO (n = 8)

 

CI (l/min/m2)

4.3 (3.8, 4.6)

3.8 (3.4, 4.1)

4.4 (4.2, 5.4)

0.073

∆CI (%)

8.8 (0, 19)

20.2 (13.2, 32.6)

−5.1 (-8.7, 6.4)

0.028

∆SVI (%)

6.4 (-6.5, 19.7)

26.0 (19.6, 32.0)

−4.0 (-11.4, 6.4)

0.004

SVI (ml/m2)

38 (33, 45)

35 (30, 40)

41 (35, 48)

0.283

SVV (%)

    

VT 6 ml/kg

5 (4, 7)

6 (5, 7)

5 (4, 8)

0.461

VT 12 ml/kg

11 (9, 17)

17 (13, 19)

10 (7, 13)

0.154

VT 18 ml/kg

15 (9, 20)

20 (18, 22)

10 (8, 16)

0.073

PPV (%)

    

VT 6 ml/kg

6 (5, 7)

7 (6, 9)

6 (4, 7)

0.368

VT 12 ml/kg

14 (10, 16)

16 (14, 20)

12 (8, 15)

0.154

VT 18 ml/kg

24 (13, 31)

28 (22, 32)

19 (11, 28)

0.214

HR (bpm)

125 (118, 131)

118 (103, 118)

128 (125, 137)

0.028

MAP (mmHg)

81 (71, 87)

80 (75, 86)

81 (68, 94)

1

CVP (mmHg)

11 (10, 13)

11 (10, 13)

11 (10, 16)

0.808

SVRI

1231 (1044,1495)

1382 (1150,1657)

1160 (985,1368)

0.368

  1. Presented as median and 25th and 75th percentile range. (CI Cardiac index, l/min/m2; SVI stroke volume index, ml/m2; SVV stroke volume variation, %, PPV pulse pressure variation, %, V T Tidal Volume, ml/kg, HR Heart rate, bpm, MAP mean arterial pressure, mmHg, CVP central venous pressure, mmHg SVRI systemic vascular resistance index, dynes-sec/cm−5/m2)
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