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Fig. 1 | BMC Anesthesiology

Fig. 1

From: Feasibility of neurally adjusted positive end-expiratory pressure in rabbits with early experimental lung injury

Fig. 1

Schematic depiction of the order of procedures for each condition. Panel a For each condition, a tNAVA level titration was initially performed (see text for details). The same assist level was used for cNAVA. tNAVA and cNAVA were alternated, every 3 min, and repeated 3 times (3 “rounds”). Arterial blood gas samples were taken after 3 min of tNAVA, and after 3 min of cNAVA, only for round 1. Panel b and c Tracings of ventilator pressure (Pvent) and electrical activity of the diaphragm (EAdi) from one representative animal breathing on tNAVA (B) and cNAVA (C). Light green shading: neural inspiration; grey: pressure delivered during neural exhalation. Horizontal dashed line indicates expiratory pressure level (visual estimation) to demonstrate the higher pressure during cNAVA. INV-RES1 = Invasive ventilation with added resistive load; INV-CO2 = Invasive ventilation with CO2 blended in to air supply/medical air; INV-ALI = invasive ventilation with acute lung injury; NIV-RES2 = Non-invasive ventilation with added resistive load; NIV-CO2 = Non-invasive ventilation with CO2 blended in to air supply/medical air; NIV-ALI = Non-invasive ventilation after acute lung injury

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