TY - JOUR AU - Liu, Ling AU - Takahashi, Daijiro AU - Qui, Haibo AU - Slutsky, Arthur S. AU - Sinderby, Christer AU - Beck, Jennifer PY - 2015 DA - 2015/09/14 TI - Feasibility of neurally adjusted positive end-expiratory pressure in rabbits with early experimental lung injury JO - BMC Anesthesiology SP - 124 VL - 15 IS - 1 AB - During conventional Neurally Adjusted Ventilatory Assist (NAVA), the electrical activity of the diaphragm (EAdi) is used for triggering and cycling-off inspiratory assist, with a fixed PEEP (so called “Triggered Neurally Adjusted Ventilatory Assist” or “tNAVA”). However, significant post-inspiratory activity of the diaphragm can occur, believed to play a role in maintaining end-expiratory lung volume. Adjusting pressure continuously, in proportion to both inspiratory and expiratory EAdi (Continuous NAVA, or cNAVA), would not only offer inspiratory assist for tidal breathing, but also may aid in delivering a “neurally adjusted PEEP”, and more specific breath-by-breath unloading. SN - 1471-2253 UR - https://doi.org/10.1186/s12871-015-0103-z DO - 10.1186/s12871-015-0103-z ID - Liu2015 ER -