Table 2 Number of nausea and vomiting over time in the three study groups (n = 105)
Palonosetron group, n = 35 (%) | Granisetron group, n = 35 (%) | Ramosetron group, n = 35 (%) | P-value | |
|---|---|---|---|---|
0-6 h | ||||
Nausea | 6 (17.1) | 5 (14.2) | 6 (17.1) | 0.87 |
Vomiting | 1 (2.9) | 0 (0) | 1 (2.9) | N/A |
Rescue drug | 2 (5.7) | 1 (2.9) | 1 (2.9) | 0.69 |
6-24 h | ||||
Nausea | 3 (8.6) | 4 (11.4) | 4 (11.4) | 0.73 |
Vomiting | 1 (2.9) | 0 (0) | 0 (0) | N/A |
Rescue drug | 1 (2.9) | 0 (0) | 0 (0) | N/A |
24-48 h | ||||
Nausea | 2 (5.7) | 1(2.9) | 1 (2.9) | 0.43 |
Vomiting | 0 (0) | 0 (0) | 0 (0) | N/A |
Rescue drug | 0 (0) | 0 (0) | 0 (0) | N/A |
No. complete responder | 21, 60.0 % | 24, 68.6 % | 26,74.3 % | 0.086 |