From: Early hyperlactatemia predicts pancreatic fistula after surgery
No Fistula (n = 66) | Fistula (n =28) | p value | |
---|---|---|---|
Postoperative baseline lactate (mmol/L)a | 1.9 (1.8) | 2.1 (1.6) | 0.64 |
6 h postoperative lactate (mmol/L)a | 1.8 (1.3) | 2.8 (2.5) | 0.04 |
12 h postoperative lactate (mmol/L)a | 1.7 (1.1) | 1.8 (1.4) | 0.81 |
Hyperlactatemia (blood lactate ≥ 2.5 mmol/L)b | 18 (27 %) | 17 (60 %) | 0.002 |
Vasopressor useb | 8 (13 %) | 7 (25 %) | 0.13 |
Cumulative norepinephrine dose (μg/kg)a | 57 (43) | 48 (12) | 0.18 |
Fluid intake during first 24 h (mL/kg)a | 46.2 (34) | 48.1 (43) | 0.15 |
Fluid balance during first 24 h (mL)a | 2160 (2000) | 2631 (2339) | 0.34 |
Intraoperative fluid requirements (mL/kg)a | 52.6 (25) | 49 (22) | 0.39 |
Red blood cells transfusions during first 24 h (mL)a | 164 (250) | 359 (530) | 0.027 |
Hemoglobin after first 24 h (g/dL)c | 10.4 ± 1.8 | 10.8 ± 1.5 | 0.35 |
APACHE II scorea | 12 (6) | 12.5 (8) | 0.98 |
Duration of operation (minutes)c | 356 ± 96 | 316 ± 94 | 0.91 |