Fig. 1
From: Cytidine-5-diphosphocholine reduces microvascular permeability during experimental endotoxemia
Experimental protocol. Intravital microscopic measurements (IVM) were performed at 0-, 60-, and 120- min in endotoxemic and nonendotoxemic animals following a stabilization period after surgical preparation. LPS (4 mg/kg/h) or an equivalent volume of saline was continuously infused starting directly after baseline IVM at 0 min. CDP-choline (100 mg/kg) was applied as an i.v. bolus in treatment groups. All administered fluids were calculated to guarantee that all animals received equal amounts of intravenous fluids. The color and number code of the experimental groups introduced in this figure is used in all other figures