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Table 2 PONV outcomes

From: Haloperidol dose combined with dexamethasone for PONV prophylaxis in high-risk patients undergoing gynecological laparoscopic surgery: a prospective, randomized, double-blind, dose-response and placebo-controlled study

 

Group H0

Group H1

Group H2

 
 

(n = 50)

(n = 49)

(n = 50)

P*

Early time (0–2 h)

    

 Nausea

15 (30 %)

5 (10 %)†

9 (18 %)

0.04

 Vomiting

7 (14 %)

3 (6 %)

4 (8 %)

0.37

 Total PONV

17 (34 %)

5 (10 %)†

10 (20 %)

0.02

 Rescue anti-emetics

12 (24 %)

3 (6 %)†

6 (12 %)

0.03

Late time (2–24 h)

    

 Nausea

17 (34 %)

10 (20 %)

9 (18 %)

0.13

 Vomiting

6 (12 %)

5 (10 %)

3 (6 %)

0.57

 Total PONV

21 (42 %)

11 (22 %)

10 (20 %)

0.03

 Rescue anti-emetics

11 (22 %)

7 (14 %)

7 (14 %)

0.48

  1. Values are numbers (proportion). Groups H0 = saline, H1 = haloperidol 1 mg, and H2 = haloperidol 2 mg
  2. PONV postoperative nausea and vomiting
  3. *Unadjusted P value
  4. P < 0.017, compared with group H0