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Table 1 ROTEM-EXTEM and laboratory coagulation parameters in examined patients

From: Tracheostomy in intensive care unit patients can be performed without bleeding complications in case of normal thromboelastometry results (EXTEM CT) despite increased PT-INR: a prospective pilot study

EXTEM parameters INR 1.21-1.29 (mean ± SD) INR ≥ 1.3 (mean ± SD) Nonsepsis (mean ± SD) Sepsis (mean ± SD)
CT (seconds) 58.60 ± 14.01 60.79 ± 7.58 ns 58.75 ± 10.42 61.92 ± 7.29 ns
CFT (seconds) 50.40 ± 21.41 67.05 ± 24.98 ns 71.17 ± 27.75 56.00 ± 19.8 ns
α angle (degrees) 80.60 ± 4.04 76.79 ± 4.67 ns 76.50 ± 5.27 78.67 ± 4.8 ns
A10 (mm) 69.00 ± 9.67 65.16 ± 8.02 ns 62.75 ± 8.98 69.17 ± 6.44 p=0.056
MCF (mm) 73.2 ± 8.17 70.47 ± 6.02 ns 68.33 ± 6.91 73.75 ± 4.75 *
LI30 (%) 99.60 ± 0.55 99.63 ± 0.59 ns 99.58 ± 0.67 99.67 ± 0.49 ns
LI60 (%) 94.00 ± 4.12 96.47 ± 3.47 ns 93.50 ± 3.56 98.42 ± 1.51 ***
ML (%) 9.00 ± 5.61 6.21 ± 4.93 ns 9.67 ± 4.89 3.92 ± 3.48 **
Laboratory parameters
Fibrinogen g/L 4.57 ± 0.88 4.73 ± 6.62 ns 4.72 ± 0.53 4.68 ± 0.79 ns
Platelets(x109/L) 209.4 ± 132.5 160.1 ± 77.18 ns 164.8 ± 101.1 175.9 ± 81.99 ns
  1. CT – coagulation time, time from the start of the sample run to the first detectable clot formation (amplitude =2 mm); CFT – clot formation time, time from CT to the clot amplitude of 20 mm (to specify the kinetics of the clot development); α angle, angle between the trace and the x-axis; A10 clot firmness (in mm amplitude) at the respective, time point after CT
  2. MCF- maximum clot firmness; LI30 and LI60 - Lysis Index at time 30 and 60 min after CT; ML - maximum lysis during whole measuring time of (90 min)
  3. Normal values for ROTEM: EXTEM – CT 38–79 s, CFT 34–159 s, α angle 63-83°, MCF 50–72 mm, LI30 0-7 %, LI60 0-15 %; Fibrinogen- 1.8-4.2 g/L, Platelets count – 150-400x109/L
  4. ns - means nonsignificant difference between two groups p > 0.05 * means significant difference between two groups p < 0.05 ** means significant difference between two groups p < 0.01 *** means significant difference between 2 groups p < 0.001