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Table 3 Hemodynamic and laboratory data and use of fluids and catecholamines

From: Effects of hypertonic saline and mannitol on cortical cerebral microcirculation in a rabbit craniotomy model

  Before osmotherapy After osmotherapy
  Group HTS (n = 8) Group MTL (n = 8) P Group HTS (n = 8) Group MTL (n = 8) P
MAP (mmHg) 56 ± 7 56 ± 4 0.9449 55 ± 5 54 ± 7 0.7726
Heart rate (beats/min) 206 ± 13 213 ± 9 0.2439 210 ± 16 215 ± 7 0.4281
pH 7.34 ± 0.15 7.35 ± 0.19 0.8466 7.34 ± 0.1 7.33 ± 0.2 0.9044
PaCO2 (kPa) 6.86 ± 2.64 6.39 ± 2.71 0.7408 7.57 ± 2.47 7.25 ± 4.58 0.8644
PaO2 (kPa) 24.3 ± 9.5 22.5 ± 10.0 0.7151 23.3 ± 9.4 23.0 ± 9.7 0.9503
HCO3- (mmol/l) 26.6 ± 5.2 25.7 ± 3.8 0.6918 30.3 ± 4.2 26.9 ± 8.0 0.3139
Hemoglobin (g/l) 94.5 ± 6.3 91.9 ± 10.3 0.5523 97.1 ± 5.2 94.5 ± 21.1 0.7383
Sodium (mmol/l) 139.0 ± 0.9 138.6 ± 1.2 0.4365 142.2 ± 2.0* 137.5 ± 7.7 0.0001
Potassium (mmol/l) 3.2 ± 0.4 3.6 ± 0.7 0.1353 3.6 ± 0.5 3.8 ± 0.5 0.6041
Chlorides (mmol/l) 104.9 ± 1.9 104.0 ± 4.2 0.5845 107.0 ± 2.2 103.5 ± 5.5 0.1154
Glucose (mmol/l) 12.4 ± 2.3 13.8 ± 3.6 0.3811 13.1 ± 4.4 13.7 ± 7.1 0.8583
Lactate (mmol/l) -- --   2.96 ± 3.97 3.00 ± 1.70 0.9808
Infused fluids (ml) -- --   42 ± 9 44 ± 10 0.6266
Number of animals recieving catechalamines 2 4 0.6038 2 4 0.6038
Highest dose of catechoalmines (μg/h) 0.00 (0.00;0.30) 0.25 (0.00;3.00) 0.4418 0.00 (0.00;0.30) 0.25 (0.00;3.00) 0.4418
  1. MAP mean arterial pressure, HTS hypertonic saline, MTL mannitol
  2. *P < 0.05 vs Before osmotherapy