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Table 3 Hemodynamic and laboratory data and use of fluids and catecholamines

From: Effects of hypertonic saline and mannitol on cortical cerebral microcirculation in a rabbit craniotomy model

 

Before osmotherapy

After osmotherapy

 

Group HTS (n = 8)

Group MTL (n = 8)

P

Group HTS (n = 8)

Group MTL (n = 8)

P

MAP (mmHg)

56 ± 7

56 ± 4

0.9449

55 ± 5

54 ± 7

0.7726

Heart rate (beats/min)

206 ± 13

213 ± 9

0.2439

210 ± 16

215 ± 7

0.4281

pH

7.34 ± 0.15

7.35 ± 0.19

0.8466

7.34 ± 0.1

7.33 ± 0.2

0.9044

PaCO2 (kPa)

6.86 ± 2.64

6.39 ± 2.71

0.7408

7.57 ± 2.47

7.25 ± 4.58

0.8644

PaO2 (kPa)

24.3 ± 9.5

22.5 ± 10.0

0.7151

23.3 ± 9.4

23.0 ± 9.7

0.9503

HCO3- (mmol/l)

26.6 ± 5.2

25.7 ± 3.8

0.6918

30.3 ± 4.2

26.9 ± 8.0

0.3139

Hemoglobin (g/l)

94.5 ± 6.3

91.9 ± 10.3

0.5523

97.1 ± 5.2

94.5 ± 21.1

0.7383

Sodium (mmol/l)

139.0 ± 0.9

138.6 ± 1.2

0.4365

142.2 ± 2.0*

137.5 ± 7.7

0.0001

Potassium (mmol/l)

3.2 ± 0.4

3.6 ± 0.7

0.1353

3.6 ± 0.5

3.8 ± 0.5

0.6041

Chlorides (mmol/l)

104.9 ± 1.9

104.0 ± 4.2

0.5845

107.0 ± 2.2

103.5 ± 5.5

0.1154

Glucose (mmol/l)

12.4 ± 2.3

13.8 ± 3.6

0.3811

13.1 ± 4.4

13.7 ± 7.1

0.8583

Lactate (mmol/l)

--

--

 

2.96 ± 3.97

3.00 ± 1.70

0.9808

Infused fluids (ml)

--

--

 

42 ± 9

44 ± 10

0.6266

Number of animals recieving catechalamines

2

4

0.6038

2

4

0.6038

Highest dose of catechoalmines (μg/h)

0.00 (0.00;0.30)

0.25 (0.00;3.00)

0.4418

0.00 (0.00;0.30)

0.25 (0.00;3.00)

0.4418

  1. MAP mean arterial pressure, HTS hypertonic saline, MTL mannitol
  2. *P < 0.05 vs Before osmotherapy