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Table 2 Microcirculatory parameters

From: Effects of hypertonic saline and mannitol on cortical cerebral microcirculation in a rabbit craniotomy model

 

Before osmotherapy

After osmotherapy

 

Group HTS (n = 8)

Group MTL (n = 8)

P

Group HTS (n = 8)

Group MTL (n = 8)

P

SVD (mm.mm−2)

7.44 ± 3.01

6.55 ± 2.36

0.5216

6.82 ± 1.95

5.86 ± 1.34

0.2699

TVD (mm.mm−2)

10.60 ± 2.44

10.06 ± 2.41

0.6636

9.99 ± 2.45

8.04 ± 2.00

0.1022

PSVD (mm.mm−2)

7.33 ± 2.95

6.43 ± 2.18

0.4978

6.70 ± 2.06

4.51 ± 2.00

0.0474

PVD (mm.mm−2)

10.37 ± 2.52

9.88 ± 2.45

0.7021

9.75 ± 2.60

6.73 ± 2.89*

0.0457

PPV (%)

97.1 ± 3.9

98.1 ± 3.1

0.5900

96.9 ± 4.7

79.8 ± 22.5*

0.0541

MFI

3.00 (2.97;3.00)

2.95 (2.79;3.00)

0.3282

3.00 (2.98;3.01)

2.66 (2.52;2.88)

0.0207

DeBacker score (mm−1)

6.59 ± 1.33

6.43 ± 1.57

0.8247

6.49 ± 1.58

5.32 ± 1.14

0.1128

  1. SVD small vessel density, TVD total vessel density, PSVD perfused small vessel density, PVD perfused vessel density, PPV proportion of perfused vessels, MFI microvascular flow index, HTS hypertonic saline, MTL mannitol
  2. *P < 0.05 vs Before osmotherapy