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Table 1 Protocol for Vancomycin administration in use in our department

From: Evaluation of a protocol for vancomycin administration in critically patients with and without kidney dysfunction

CLINICAL PROTOCOL
STARTING LOADING DOSE:
if body weight < 65 Kg = 1000 mg  
if body weight ≥ 65 Kg = 1500 mg  
DAILY DOSE:
Creatinine clearance Vancomycin daily dose
>50 ml/min/1,73 m2 2000 mg
50-20 ml/min/1,73 m2 1500 mg
20-10 ml/min/1,73 m2 1000 mg
<10 ml/min/1,73 m2 500 mg
DOSE ADJUSTMENT AFTER VANCOMYCIN SERUM CONCENTRATION (VSC) MEASUREMENT:
VSC Adjustment dose
<15 mg/L Increase infusion 500 mg/day
15-25 mg/L Do not change infusion
25-30 mg/L Riduce infusion 500 g/day
>30 mg/L Stop infusion for 6 h, than riduced dose