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Figure 6 | BMC Anesthesiology

Figure 6

From: Epinephrine reversed high-concentration bupivacaine- induced inhibition of calcium channels and transient outward potassium current channels, but not on sodium channel in ventricular myocytes of rats

Figure 6

The Ito current-voltage relationship in the absence of bupivacaine, with 100 μmol/L bupivacaine alone, and 100 μmol/L bupivacaine in combination with epinephrine 0.15 μg/ml. Bupivacaine 100 μmol/L without epinephrine decreased Ito. On the other hand, Ito increased in response to the bupivacaine 100 μmol/L in combination with epinephrine 0.15 μg/ml.

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