Table 4 MTH phases

Died (n)

21

(41%)

23

(37%)

NT-proBNP

NT-proBNP, start induction (ng/l)

1981

(483–4217)

303

(116–1331)*†

NT-proBNP, start maintenance (ng/l)

2011

(720–4239)†

588

(213–1710)*†

NT-proBNP, end maintenance (ng/l)

1297

(454–3761)†

1591

(476–3448)

NT-proBNP, end rewarming (ng/l)

747

(287–2037)

1681

(472–3383)

Induction phase

paO₂ (mmHg)

96

(75–129)

88

(72–111)

sO₂ (%)

97

(93–99)

97

(93–99)

Lactate (μgl/L)

2.0

(1.2–2.6)

2.5

(1.4–4.4)

Leukocyte count (10^9/L)

14.0

(11.3–18.5)

17.7

(12.3–21.8)

Heart Rate (bpm)

68

(58–76)

73

(59–91)

Systolic blood pressure (mmHg)

114

(104–129)

106

(100–117)*

Diastolic blood pressure (mmHg)

60

(57–68)

62

(54–69)

Noradrenaline (mg)

0.44

(0.02–1.15)

0.39

(0.08–1.11)

Diuresis (ml/hour)

74

(34–144)

67

(35–150)

Maintenance phase

paO₂ (mmHg)

86

(73–112)

88

(73–107)

sO₂ (%)

97

(94–99)

96

(94–98)

Lactate (μgl/L)

1.4

(1.0–2.2)

2.1

(1.4–3.4)*

Leukocyte count (10^9/L)

10.4

(7.6–13.6)

13.0

(9.8–16.6)*

Heart Rate (bpm)

57

(48–66)

61

(50–71)

Systolic blood pressure (mmHg)

109

(104–117)

105

(101–111)

Diastolic blood pressure (mmHg)

57

(53–60)

57

(53–62)

Noradrenaline (mg)

0.61

(0.23–1.20)

0.60

(0.15–1.19)

Diuresis (ml/hour)

77

(44–123)

72

(34–116)

Rewarming phase

paO₂ (mmHg)

85

(74–100)

88

(76–102)

sO₂ (%)

97

(95–98)

97

(93–98)

Lactate (μgl/L)

1.3

(0.9–2.1)

2.0

(1.5–2.8)*

Leukocyte count (10^9/L)

10.4

(7.5–15.2)

11.1

(9.2–16.3)

Heart Rate (bpm)

72

(63–85)

75

(66–86)

Systolic blood pressure (mmHg)

108

(100–115)

109

(100–119)

Diastolic blood pressure (mmHg)

55

(52–59)

55

(51–59)

Noradrenaline (mg)

0.81

(0.11–1.29)

0.61

(0.17–1.60)

Diuresis (ml/hour)

42

(30–68)

38

(21–86)