Figure 3

Box plot for temporal trend in VDI for the first TPE treatment of every patient. The time points extend from less than 1 hour before TPE (pre treatment), through every hour of TPE (treatment 1 hr, 2 hr etc.) to 12 hours after TPE (post treatment 1 hr, 2 hr etc.). N.B. only a few TPE were as long as 4 or 5 hours so the data values for treatment 4 hr and 5 hr are calculated from only a few TPE treatments.