Figure 5
From: Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats
PBF and density ratios for ROIspecific. Data from PET and CT images representing the PBF and density fraction of injured to uninjured lung for a region of interest (ROIspecific) in all of the injured animals in the present study (2 hours after injury; n = 5) and a previous study (n = 12) [11] in which the spatial PBF distribution was measured 10 minutes after acid aspiration injury. The data are shown as the median [25th and 75th percentiles] and the minimum to maximum values. The ROIspecific was spherical and of identical size (0.24 cm3) for all animals and for the PET and CT images of each animal. For the mean density values (CT images) and for the mean radioactivity concentration values (PET images), the presented fractions were calculated using the quotient of the ROIspecific values for the injured side versus that of the non-injured side of each animal. A greater mean density on the injured side resulted in a CT quotient > 1 in the ROIspecific. Lower mean concentrations of Ga-68 microspheres on the injured side 2 hours after injury yielded a PET quotient < 1 in the ROIspecific, whereas higher mean concentrations of Ga-68 microspheres on the injured side 10 minutes after injury yielded a PET quotient > 1 in the ROIspecific.