From: Required propofol dose for anesthesia and time to emerge are affected by the use of antiepileptics: prospective cohort study
No antiepileptic
Antiepileptic
P-value
Dose of propofol (mg/kg/h)
6.8 ± 1.27
5.7 ± 1.51
<0.0001
Concentration at emergence (μg/ml)
0.7 ± 0.02
0.5 ± 0.03
Time to emerge (min)
21.6 ± 10.0
29.5 ± 12.5