Table 1 Gas exchange, respiratory and arteriovenous extracorporeal lung assist parameters, before and after lung injury, post recruitment and during the time course
TBaseline | TARDS | TRM | 3 Hz/ECLA | 3 Hz | 6 Hz/ECLA | 6 Hz | |
|---|---|---|---|---|---|---|---|
RR | 30+/-0 | 30+/-0 | 180+/-0§ | 180+/-0§ | 180+/-0§ | 360+/-0§ | 360+/-0§ |
mPaw | 9.3+/-0.4§ | 13.2+/-1.4 | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ |
FiO2 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 |
pHa | 7.45+/-0.09 | 7.41+/-0.06 | 7.55+/-0.04§ | 7.6+/-0.04§ | 7.58+/-0.07§ | 7.48+/-0.07 | 7.4+/-0.08* |
PaO2 | 585+/-24§ | 60+/-12 | 532+/-116§ | 563+/-69§ | 551+/-75§ | 549+/-68§ | 556+/-60§ |
PaCO2 | 37.7+/-4.2 | 42.7+/-5.3 | 27.7+/-3.5§ | 27.1+/-6§ | 26.3+/-5.3§ | 34+/-4.6 | 44.6+/-12.5* |
SvO2 | 86.1+/-4.1§ | 67.9+/-6.1 | 85.5+/-2.7§ | 89.1+/-3.2§ | 82.4+/-6.3§ | 86.8+/-3.7§ | 76.8+/-6.7§* |
DO2 | 906+/-295 | 739+/-251 | 919+/-223 | 920+/-198 | 706+/-189* | 804+/-192 | 593+/-211* |
VO2 | 197+/-35 | 169+/-30 | 214+/-34§ | 192+/-31 | 184+/-31 | 182+/-39 | 182+/-38 |
Qs/Qt | 0.07+/-0.02§ | 0.54+/-0.09 | 0.12+/-0.09§ | 0.11+/-0.07§ | 0.1+/-0.06§ | 0.11+/-0.06§ | 0.07+/-0.04§* |
Plow | 5.8+/-0.5§ | 19.6+/-1.1 | |||||
PECLAO2 | 564+/-36 | 574+/-45 | |||||
SGF | 0+/-0 | 2.4+/-2.3 | |||||
EBF | 1.4+/-0.2 | 1.4+/-0.2 | |||||
EBF/CO | 21+/-6 | 25+/-6 | |||||
9 Hz/ECLA | 9 Hz | 12 Hz/ECLA | 12 Hz | 15 Hz/ECLA | 15 Hz | End | |
RR | 540+/-0§ | 540+/-0§ | 720+/-0§ | 720+/-0§ | 900+/-0§ | 900+/-0§ | 180+/-0§ |
mPaw | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ | 22.6+/-1.1§ |
FiO2 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 | 1.0+/-0 |
pHa | 7.46+/-0.05 | 7.34+/-0.08* | 7.45+/-0.05 | 7.29+/-0.08* | 7.43+/-0.06 | 7.26+/-0.07* | 7.54+/-0.05§ |
PaO2 | 554+/-74§ | 553+/-56§ | 557+/-71§ | 542+/-59§ | 550+/-53§ | 508+/-70§S* | 579+/-25§ |
PaCO2 | 37.5+/-4 | 53.2+/-13.3§* | 39+/-4.2 | 61.1+/-13.7§* | 39.9+/-5.5 | 66.8+/-12.7§* | 29.5+/-3.6§ |
SvO2 | 86.5+/-3.1§ | 74.2+/-5.5§* | 86.1+/-3.2§ | 75.5+/-4§* | 85.3+/-4§ | 75.7+/-7§* | 80.7+/-4.5§ |
DO2 | 764+/-152 | 538+/-118* | 767+/-110 | 558+/-135* | 819+/-194 | 590+/-169* | 616+/-76 |
VO2 | 177+/-38 | 181+/-32 | 180+/-34 | 181+/-36 | 194+/-33 | 182+/-29 | 178+/-38 |
Qs/Qt | 0.1+/-0.07§ | 0.06+/-0.03§* | 0.1+/-0.07§ | 0.06+/-0.04§* | 0.1+/-0.05§ | 0.08+/-0.04§ | 0.08+/-0.03§ |
Plow | 20.7+/-3.5 | ||||||
PECLAO2 | 608+/-36 | 628+/-22 | 620+/-28 | ||||
SGF | 3.9+/-4.1 | 5+/-4 | 5+/-4.1 | ||||
EBF | 1.5+/-0.2 | 1.4+/-0.2 | 1.4+/-0.3 | ||||
EBF/CO | 27+/-6 | 26+/-2 | 24+/-4 |