The impact of administration of tranexamic acid in reducing the use of red blood cells and other blood products in cardiac surgery

Table 7 Multivariate analysis of the effect of administration of Tranexamic acid on the outcomes of interest.

Risk	Odds Ratio (95% CI)	p value
RBC transfusion	0.58 (0.47 – 0.71)	< 0.001
FFP transfusion	0.57 (0.43 – 0.75)	< 0.001
Any blood product transfusion	0.58 (0.48 – 0.71)	<0.001
Return to theatre	0.44 (0.32 – 0.60)	<0.001
ICU stay	0.83 (0.67 – 1.04)	0.100

Multivariate analysis of the effect of administration of Tranexamic acid on the outcomes of interest. The multivariate analysis showed that the odds of receiving a transfusion of any type of product, or returning to theatre for bleeding, were less in patients in tranexamic acid group. (RBC – red blood cells, FFP – fresh frozen plasma, ICU – intensive care unit, CI – confidence interval) (* = p value < 0.05, statistically significant)

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