The impact of administration of tranexamic acid in reducing the use of red blood cells and other blood products in cardiac surgery

Table 6 Effect of Surgeon and Anaesthetist on outcomes of interest.

	Surgeon		Anaesthetist
Variable	Range (as %)	Overall p value	Range (as %)	Overall p value
TA administration	--	--	56 – 90	<0.001
RBC transfusion	41 – 51	0.007	41 – 52	0.028
FFP transfusion	5 – 15	<0.001	7 – 11	0.573
Any blood products transfusion	41 – 53	0.002	42 – 53	0.019
Return to theatre	3.6 – 8.1	0.011	3.5 – 7.6	0.146
ICU stay (> one day)	17 – 33	<0.001	17 – 27	0.005

Effect of Surgeon and Anaesthetist on outcomes of interest. The surgeon had an influence on the rate of transfusion of red blood cells, fresh frozen plasma and all blood products, the rate of return to theatre for bleeding and the rate of intensive care stay longer than one day. The anaesthetist had an influence on the rate of tranexamic acid administration, the rate of transfusion of red blood cells and all blood products and the rate of intensive care stay longer than one day. (TA – Tranexamic acid, RBC – red blood cells, FFP – fresh frozen plasma, ICU – intensive care unit, Range – proportion of patients among various surgeons and anaesthetists) (* = p value < 0.05, statistically significant)

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