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Table 2 Variables of Gas exchange during recruitment manoeuvre.

From: Sustained inflation and incremental mean airway pressure trial during conventional and high-frequency oscillatory ventilation in a large porcine model of acute respiratory distress syndrome

 

Group

T baseline

TALI

T15

T30

T45

T60

Number of

PCV

9

9

9

9

9

9

animals

HFOV

9

9

9

9

9

9

pHa

PCV

7.45 ± 0.06***

7.32 ± 0.06

7.31 ± 0.06

7.33 ± 0.05

7.34 ± 0.06

7.34 ± 0.06

 

HFOV

7.48 ± 0.09***

7.35 ± 0.04

7.43 ± 0.05*+

7.45± 0.06**+

7.45 ± 0.05**+

7.44 ± 0.05*+

DO 2

PCV

794 ± 312

781 ± 216

740 ± 145

722 ± 133

677 ± 114

644 ± 110

(ml/min/m 2 )

HFOV

662 ± 157

724 ± 152

710 ± 105

677 ± 99

624 ± 117

547 ± 59*

VO 2

PCV

184 ± 42*

221 ± 72

   

194 ± 44

(ml/min/m 2 )

HFOV

165 ± 37*

204 ± 52

   

188 ± 24

SvO 2

PCV

83 ± 6***

60 ± 14

   

69 ± 10*

[%]

HFOV

84 ± 3***

62 ± 8

   

72 ± 5**

mPaw

PCV

10 ± 1***

15 ± 2

18 ± 2***

20 ± 2***

23 ± 2***

26 ± 2***

[cmH2O]

HFOV

9 ± 0***

15 ± 1

18 ± 1***

21 ± 1***

24 ± 1***

27 ± 1***

PIP

PCV

15 ± 1***

25 ± 3

27 ± 3***

28 ± 3***

30 ± 3***

33 ± 3***

[cmH2O]

HFOV

14 ± 1***

25 ± 2

20 ± 1***+

23 ± 1***+

26 ± 1***+

29 ± 1***+

 

Group

T 75

T 90

T 105

T 120

T 135

T 150

Number of

PCV

9

9

9

9

7

4

animals

HFOV

9

8

7

3

  

pHa

PCV

7.35 ± 0.06

7.35 ± 0.05

7.35 ± 0.05

7.33 ± 0.05

7.31 ± 0,06

7.30 ± 0,04

 

HFOV

7.43 ± 0.04*+

7.41± 0.05

7.39 ± 0.04

7.38 ± 0.04

  

DO 2

PCV

591 ± 71*

571 ± 68

551 ± 65

506 ± 73

494 ± 89

475 ± 74

(ml/min)

HFOV

503 ± 71**

461 ± 72

478 ± 60

489 ± 92

  

VO 2

PCV

   

183 ± 27

  

(ml/min)

HFOV

   

194 ± 18

  

SvO2

PCV

   

70 ± 4

  

[%]

HFOV

   

66 ± 9

  

mPaw

PCV

28 ± 1***

31 ± 2

34 ± 1

36 ± 2

37 ± 4

36 ± 2

[cmH2O]

HFOV

29 ± 2***

32 ± 3

33 ± 4

33 ± 1

  

PIP

PCV

35 ± 2***

38 ± 2

42 ± 3

43 ± 4

45 ± 6

45 ± 2

[cmH2O]

HFOV

31 ± 2***+

34 ± 3

35 ± 4

35 ± 1

  
  1. Data are mean ± standard deviation; Two-way-ANOVA with repeated measurements (Student-Newman-Keuls post hoc test): * p < 0.05, ** p < 0.01, *** p < 0.001 vs. TAli; HFOV compared with PCV: + p < 0.001. PCV = pressure controlled ventilation; HFOV = High-frequency oscillatory ventilation; DO2 = oxygen delivery; VO2 = oxygen consumption; SvO2 = mixed venous oxygen saturation; mPaw = mean pulmonary airway pressure; PIP = peak pulmonary airway pressure.