Group | T baseline | TALI | T15 | T30 | T45 | T60 | |
---|---|---|---|---|---|---|---|
Number of | PCV | 9 | 9 | 9 | 9 | 9 | 9 |
animals | HFOV | 9 | 9 | 9 | 9 | 9 | 9 |
pHa | PCV | 7.45 ± 0.06*** | 7.32 ± 0.06 | 7.31 ± 0.06 | 7.33 ± 0.05 | 7.34 ± 0.06 | 7.34 ± 0.06 |
HFOV | 7.48 ± 0.09*** | 7.35 ± 0.04 | 7.43 ± 0.05*+ | 7.45± 0.06**+ | 7.45 ± 0.05**+ | 7.44 ± 0.05*+ | |
DO 2 | PCV | 794 ± 312 | 781 ± 216 | 740 ± 145 | 722 ± 133 | 677 ± 114 | 644 ± 110 |
(ml/min/m 2 ) | HFOV | 662 ± 157 | 724 ± 152 | 710 ± 105 | 677 ± 99 | 624 ± 117 | 547 ± 59* |
VO 2 | PCV | 184 ± 42* | 221 ± 72 | 194 ± 44 | |||
(ml/min/m 2 ) | HFOV | 165 ± 37* | 204 ± 52 | 188 ± 24 | |||
SvO 2 | PCV | 83 ± 6*** | 60 ± 14 | 69 ± 10* | |||
[%] | HFOV | 84 ± 3*** | 62 ± 8 | 72 ± 5** | |||
mPaw | PCV | 10 ± 1*** | 15 ± 2 | 18 ± 2*** | 20 ± 2*** | 23 ± 2*** | 26 ± 2*** |
[cmH2O] | HFOV | 9 ± 0*** | 15 ± 1 | 18 ± 1*** | 21 ± 1*** | 24 ± 1*** | 27 ± 1*** |
PIP | PCV | 15 ± 1*** | 25 ± 3 | 27 ± 3*** | 28 ± 3*** | 30 ± 3*** | 33 ± 3*** |
[cmH2O] | HFOV | 14 ± 1*** | 25 ± 2 | 20 ± 1***+ | 23 ± 1***+ | 26 ± 1***+ | 29 ± 1***+ |
Group | T 75 | T 90 | T 105 | T 120 | T 135 | T 150 | |
Number of | PCV | 9 | 9 | 9 | 9 | 7 | 4 |
animals | HFOV | 9 | 8 | 7 | 3 | ||
pHa | PCV | 7.35 ± 0.06 | 7.35 ± 0.05 | 7.35 ± 0.05 | 7.33 ± 0.05 | 7.31 ± 0,06 | 7.30 ± 0,04 |
HFOV | 7.43 ± 0.04*+ | 7.41± 0.05 | 7.39 ± 0.04 | 7.38 ± 0.04 | |||
DO 2 | PCV | 591 ± 71* | 571 ± 68 | 551 ± 65 | 506 ± 73 | 494 ± 89 | 475 ± 74 |
(ml/min) | HFOV | 503 ± 71** | 461 ± 72 | 478 ± 60 | 489 ± 92 | ||
VO 2 | PCV | 183 ± 27 | |||||
(ml/min) | HFOV | 194 ± 18 | |||||
SvO2 | PCV | 70 ± 4 | |||||
[%] | HFOV | 66 ± 9 | |||||
mPaw | PCV | 28 ± 1*** | 31 ± 2 | 34 ± 1 | 36 ± 2 | 37 ± 4 | 36 ± 2 |
[cmH2O] | HFOV | 29 ± 2*** | 32 ± 3 | 33 ± 4 | 33 ± 1 | ||
PIP | PCV | 35 ± 2*** | 38 ± 2 | 42 ± 3 | 43 ± 4 | 45 ± 6 | 45 ± 2 |
[cmH2O] | HFOV | 31 ± 2***+ | 34 ± 3 | 35 ± 4 | 35 ± 1 |