Group | T baseline | TALI | T15 | T30 | T45 | T60 | |
---|---|---|---|---|---|---|---|
Number of | PCV | 9 | 9 | 9 | 9 | 9 | 9 |
animals | HFOV | 9 | 9 | 9 | 9 | 9 | 9 |
HR | PCV | 71 ± 18 | 85 ± 22 | 85 ± 18 | 76 ± 20 | 73 ± 24 | 73 ± 23 |
[/min] | HFOV | 66 ± 9 | 79 ± 6 | 67 ± 5*+ | 63 ± 3* | 62 ± 4* | 64 ± 5* |
MAP | PCV | 75 ± 13*** | 93 ± 11 | 84 ± 17 | 86 ± 11 | 86 ± 10 | 86 ± 10 |
[mmHg] | HFOV | 71 ± 8*** | 94 ± 9 | 87 ± 7 | 87 ± 5 | 85 ± 6 | 83 ± 7** |
CVP | PCV | 4.9 ± 2.4*** | 7.1 ± 2.3 | 7.6 ± 1.8 | 8.1 ± 1.8 | 8.6 ± 2.1** | 9.4 ± 2.5*** |
[mmHg] | HFOV | 5.2 ± 2.2** | 6.4 ± 2.5 | 9.7 ± 2.0***+ | 10.4 ± 2.1***+ | 10.7± 1.9***+ | 11.9 ± 2.0***+ |
MPAP | PCV | 19 ± 5*** | 37 ± 6 | 34 ± 5*** | 31 ± 4*** | 28 ± 4*** | 30 ± 3*** |
[mmHg] | HFOV | 17 ± 2*** | 34 ± 5 | 30 ± 6**+ | 27 ± 4*** | 29 ± 4*** | 31 ± 4** |
PCWP | PCV | 7.3 ± 2.9 | 8.7 ± 2.1 | 10.2 ± 2.0 | 10.0 ± 2.3 | 12.0 ± 3.0*** | 12.6 ± 3.0*** |
[mmHg] | HFOV | 7.4 ± 1.6** | 9.7 ± 3.7 | 12.2 ± 2.8** | 13.0 ± 2.9***+ | 12.8 ± 1.8*** | 14.0 ± 1.9*** |
Qs/Qt | PCV | 0.09 ± 0.05*** | 0.54 ± 0.10 | 0.31 ± 0.17 ** | |||
(ratio) | HFOV | 0.06 ± 0.01*** | 0.52 ± 0.07 | 0.10 ± 0.04***+ | |||
Group | T 75 | T 90 | T 105 | T 120 | T 135 | T 150 | |
Number of | PCV | 9 | 9 | 9 | 9 | 7 | 4 |
animals | HFOV | 9 | 8 | 7 | 3 | ||
HR | PCV | 71 ± 18 | 74 ± 18 | 80 ± 18 | 83 ± 19 | 92 ± 18 | 100 ± 16 |
[/min] | HFOV | 67 ± 8 | 77 ± 10 | 82 ± 13 | 97 ± 13 | ||
MAP | PCV | 83 ± 7* | 79 ± 6 | 76 ± 10 | 75 ± 8 | 73 ± 9 | 77 ± 4 |
[mmHg] | HFOV | 78 ± 6*** | 77 ± 8 | 80 ± 6 | 80 ± 5 | ||
CVP | PCV | 10.4 ± 2.4*** | 11.1 ± 2.0 | 11.7 ± 2.1 | 12.7 ± 3.0 | 13.4 ± 2.3 | 14.5 ± 2.5 |
[mmHg] | HFOV | 12.8 ± 2.0***+ | 13.1 ± 1.8 | 13.4 ± 2.6 | 14.7 ± 2.9 | ||
MPAP | PCV | 32 ± 3*** | 33 ± 3 | 35 ± 4 | 37 ± 3 | 39 ± 5 | 41 ± 2 |
[mmHg] | HFOV | 32 ± 4* | 35 ± 5 | 36 ± 4 | 37 ± 4 | ||
PCWP | PCV | 13.4 ± 2.1*** | 13.6 ± 2.8 | 15.4 ± 3.1 | 17.3 ± 3.5 | 19.0 ± 2.7 | 19.3 ± 1.9 |
[mmHg] | HFOV | 15.9 ± 2.4***+ | 16.4 ± 2.5 | 16.3 ± 3.3 | 18.0 ± 2.6 | ||
Qs/Qt | PCV | 0.06 ± 0.02 | |||||
(ratio) | HFOV | 0.04 ± 0.02 |