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Table 2 Comparison of rule of 3 and exact binomial estimates of risk

From: Incidence of epidural haematoma and neurological injury in cardiovascular patients with epidural analgesia/anaesthesia: systematic review and meta-analysis

 

Number of

Lower 95% of risk

Outcome

Events

Patients

rule of 3

Exact CI

Epidural haematoma

    

Cardiac

0

4971

1 in 1,700

1 in 1,350

Thoracic

0

4108

1 in 1,400

1 in 1,100

Vacular

0

5026

1 in 1,700

1 in 1,350

Combined

0

14105

1 in 4,700

1 in 3,800

Permanent neurological injury

    

Combined

0

13827

1 in 4,600

1 in 3,750