Table 4 Age dependence of steady state fractional liver blood flow clearance (Liver Clearance), the intrinsic liver clearance (Tclr), and fraction of bolus dose sequestered in lung (frdose).
From: Human physiologically based pharmacokinetic model for propofol
Age (years) | Liver Clearance | Tclr (liters/min) | frdose |
|---|---|---|---|
29.125 | 0.772 | 165 | 0.3 |
52.5 | 0.781 | 208 | 0.06875 |
74.75 | 0.762 | 104 | 0 |