From: Individual patient meta-analysis of single-dose rofecoxib in postoperative pain
Drug and dose | Number of patients in comparison | NNT (95% CI) |
---|---|---|
Rofecoxib 50 mg | 1900 | 1.9 (1.8 to 2.1) |
Valdecoxib 40 mg1 | 473 | 1.6 (1.4 to 1.8) |
Valdecoxib 20 mg1 | 204 | 1.7 (1.4 to 2.0) |
Diclofenac 50 mg2 | 367 | 2.1 (1.8 to 2.6) |
Ibuprofen 400 mg2 | 3402 | 2.2 (2.1 to 2.4) |
Paracetamol 975/1000 mg2 | 1038 | 3.7 (3.1 to 4.7) |
Paracetamol 600/650 mg2 | 1265 | 4.2 (3.6 to 5.2) |
Aspirin 600/650 mg2 | 3635 | 4.7 (4.2 to 5.4) |