Skip to main content

Table 6 Comparison of NNTs for oral analgesics in dental pain. NNT are for at least 50% pain relief compared with placebo over six hours

From: Individual patient meta-analysis of single-dose rofecoxib in postoperative pain

Drug and dose

Number of patients in comparison

NNT (95% CI)

Rofecoxib 50 mg

1900

1.9 (1.8 to 2.1)

Valdecoxib 40 mg1

473

1.6 (1.4 to 1.8)

Valdecoxib 20 mg1

204

1.7 (1.4 to 2.0)

Diclofenac 50 mg2

367

2.1 (1.8 to 2.6)

Ibuprofen 400 mg2

3402

2.2 (2.1 to 2.4)

Paracetamol 975/1000 mg2

1038

3.7 (3.1 to 4.7)

Paracetamol 600/650 mg2

1265

4.2 (3.6 to 5.2)

Aspirin 600/650 mg2

3635

4.7 (4.2 to 5.4)

  1. 1. Barden et al. BMC Anesthesiol. 2003 3:1 2. Barden et al, BDJ, in press.