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Table 2 Rofecoxib 50 mg numbers-needed-to-treat compared with common analgesics

From: Single-dose rofecoxib for acute postoperative pain in adults: a quantitative systematic review

Drug and dose

Number of patients in the comparison

NNT (95%CI)

Rofecoxib 50 mg

675

2.3 (2.0 to 2.6)

Diclofenac 50 mg

738

2.3 (2.0 to 2.7)

Ibuprofen 400 mg

4703

2.4 (2.3 to 2.6)

Morphine 10 mg (IM)

946

2.9 (2.6 to 3.6)

Paracetamol 1000 mg

2759

3.8 (3.4 to 4.4)

Paracetamol 600/650 mg + codeine 60 mg

1123

4.2 (3.4 to 5.3)

Aspirin 600/650 mg

5061

4.4 (4.0 to 4.9)

  1. Compiled from published and unpublished systematic reviews