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Table 2 Rofecoxib 50 mg numbers-needed-to-treat compared with common analgesics

From: Single-dose rofecoxib for acute postoperative pain in adults: a quantitative systematic review

Drug and dose Number of patients in the comparison NNT (95%CI)
Rofecoxib 50 mg 675 2.3 (2.0 to 2.6)
Diclofenac 50 mg 738 2.3 (2.0 to 2.7)
Ibuprofen 400 mg 4703 2.4 (2.3 to 2.6)
Morphine 10 mg (IM) 946 2.9 (2.6 to 3.6)
Paracetamol 1000 mg 2759 3.8 (3.4 to 4.4)
Paracetamol 600/650 mg + codeine 60 mg 1123 4.2 (3.4 to 5.3)
Aspirin 600/650 mg 5061 4.4 (4.0 to 4.9)
  1. Compiled from published and unpublished systematic reviews