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Table 1 Demographic and clinical characteristics of the patients enrolled in the study

From: The role of plasma gelsolin in cardiopulmonary bypass induced acute lung injury in infants and young children: a pilot study

 

Total

ALI (n = 27)

Non-ALI (n = 50)

p

Sex male n (%)

55(71.4)

17(63.0)

38(76.0)

0.27C

Age (months)

9.1 ± 6.8

5.8 ± 4.5

10.9 ± 7.2

0.001a

Age distribution

   

0.03C

0-1 year old

54

23(42.6)

31(57.4)

 

1-2 years old

19

4(21.1)

15(78.9)

 

2-3 years old

4

0(0)

4(100)

 

Weight (kg)

7.3 ± 2.2

6.0 ± 1.8

8.0 ± 2.1

0.001a

RACHS-1

   

0.37C

1

10

3

7

 

2

63

21

42

 

≥3

4

3

1

 

CPB time (min)

69.4 ± 23.3

74.6 ± 22.1

66.7 ± 23.7

0.23a

Aortic cross clamp time (min)

50.1 ± 19.6

46.5 ± 17.7

44.2 ± 20.7

0.68a

Nadir HCT during CPB (%)

25.3 ± 2.7

25.2 ± 2.3

25.2 ± 3.0

0.98a

Positive fluid balance after CPB (%)

55(71.4)

24(88.9)

31(62.0)

0.03C

Need for transfusion within 24 hours after CPB (%)

6(7.8)

2(7.4)

4(8.0)

0.93C

Nosocomial pneumonias (%)

15(19.5)

6(22.2)

9(18.0)

0.58C

CPAP (%)

10(13.0)

9(33.3)

4(8.0)

0.04C

EF (%)

3(3.9)

3(11.1)

0(0)

0.12C

MV time (hour)

24(3 ~ 446)

26(4 ~ 446)

6.5(3 ~ 189)

0.001b

SICU stay (day)

5(2 ~ 34)

9.2 ± 6.6

4(2 ~ 34)

0.001b

Hospital stay (day)

23.4 ± 10.0

26.1 ± 11.0

21.9 ± 9.2

0.15a

Hospital death (%)

0

0

0

0.77C

  1. Continuous variables were expressed as the mean ± SD or median (interquartile range) if appropriated. Categorical variable were expressed as number of patients (%).
  2. a: Student’s t-test; b: Mann–Whitney U-test; C: χ2 test.
  3. RACHS-1 = Risk Adjusted Classification for Congenital Heart Surgery; ALI = acute lung injury; CPB = cardiopulmonary bypass; MV = mechanical ventilation; CPAP = Continuous positive airway pressure; EF = Extubation failure; SICU = surgery intensive care unit; UVR = ultrafiltered volume removal.