Table 2 Preoperative demographics and intraoperative data of patients 2 years before and after ventilator exchange
Preoperative variable | Before vent exchange (n = 15,481) | After vent exchange (n = 18,945) | p |
|---|---|---|---|
Age (mean ± SD, yr) | 50 ± 17 | 52 ± 16 | < 0.001 |
Male (n,%) | 6936 (45%) | 8619 (46%) | 0.776 |
Patient ASA 3,4 or 5 (n,%) | 4207 (27%) | 6259 (33%) | < 0.001 |
Emergent Case (n,%) | 697 (4%) | 830 (4%) | 0.605 |
Predicted Body Weight (mean ± SD, kg) | 64 ± 11 | 64 ± 11 | 0.939 |
Weight (mean ± SD, kg) | 83 ± 22 | 84 ± 22 | < 0.001 |
BMI (mean ± SD, kg/m 2 ) | 28.6 ± 6.9 | 29.1 ± 7.3 | < 0.001 |
Smoker | |||
Former (n,%) | 2717 (18%) | 4009 (21%) | < 0.001 |
Current (n,%) | 2556 (17%) | 3024 (16%) | 0.174 |
Lung Disease (n,%) | 45 (0.3%) | 59 (0.3%) | 0.802 |
Asthma (n,%) | 1153 (7%) | 1633 (9%) | < 0.001 |
COPD (n,%) | 744 (5%) | 1046 (6%) | 0.003 |
Diabetes (n,%) | 1758 (11%) | 2658 (14%) | < 0.001 |
Hypertension (n,%) | 5055 (33%) | 7409 (39%) | < 0.001 |
Coronary Artery Disease (n,%) | 1143 (7%) | 1633 (9%) | < 0.001 |
Congestive Heart Failure (n,%) | 378 (2%) | 676 (4%) | 0.545 |
Chronic Kidney Disease (n,%) | 717 (5%) | 1157 (6%) | < 0.001 |
Hepatic Disease (n,%) | 235 (2%) | 452 (2%) | < 0.001 |
Alcohol Abuse (n,%) | 535 (4%) | 582 (3%) | 0.049 |
Current Steroid Therapy (n,%) | 341 (2%) | 658 (4%) | < 0.001 |
Intraoperative variable | Before vent exchange (n = 15,481) | After vent exchange (n = 18,945) | p |
Ventilatory Parameters (case medians) | |||
PIP (mean ± SD, cmH 2 O) | 25.4 ± 5.9 | 20.2 ± 6.1 | < 0.001 |
PEEP (mean ± SD, cmH 2 O) | 1.9 ± 1.2 | 2.7 ± 2.8 | < 0.001 |
ΔP (mean ± SD, cmH 2 O) | 23.4 ± 5.7 | 17.5 ± 5.6 | < 0.001 |
RR (mean ± SD, breath per minute) | 11.0 ± 2.5 | 10.7 ± 2.5 | < 0.001 |
Vt (mean ± SD, ml) | 587 ± 146 | 543 ± 118 | < 0.001 |
Vt cc/kg PBW (mean ± SD, ml) | 9.35 ± 2.29 | 8.67 ± 1.95 | < 0.001 |
FiO 2 (mean ± SD,%) | 55.3 ± 16 | 54.1 ± 19 | < 0.001 |
cc/kg PBW ≤ 6 (n,%) | 1221 (8%) | 1643 (9%) | < 0.001 |
cc/kg PBW ≤ 8 (n,%) | 3534 (23%) | 6465 (34%) | < 0.001 |
Epochs of 10 minutes: | |||
PIP > 30 cmH2O | 3.1 ± 7.1 | 1.2 ± 4.2 | < 0.001 |
Vt > 12 cc/kg PBW | 1.92 ± 4.9 | 0.8 ± 3.4 | < 0.001 |
Colloid use (n,%) | 1585 (10%) | 1828 (10%) | 0.072 |
Crystalloid volume (median, 25 th ,75 th , ml) | 2000 (1200,3000) | 2200 (1600,3100) | < 0.001 |
Case Length (mean ± SD, minutes) | 214 ± 125 | 206 ± 122 | < 0.001 |
Transfusion (n,%) | 793 (5%) | 880 (5%) | 0.043 |
PRBC (n,%) | 727 (5%) | 810 (4%) | 0.064 |
FFP (n,%) | 175 (1%) | 159 (1%) | 0.007 |
Platelets (n,%) | 91 (0.6%) | 104 (0.5%) | 0.685 |