Table 1 Preoperative demographics and intraoperative data of patients 2 months before and after ventilator exchange
Preoperative variable | Before vent exchange (n = 1414) | After vent exchange (n = 1635) | p |
|---|---|---|---|
Age (mean ± SD, yr) | 51 ± 16 | 51 ± 16 | 0.713 |
Male (n,%) | 628 (44%) | 731 (44%) | 0.898 |
Patient ASA 3,4 or 5 (n,%) | 443 (31%) | 536 (32%) | 0.413 |
Emergent Case (n,%) | 46 (3%) | 54 (3%) | 0.980 |
Predicted Body Weight (mean ± SD, kg) | 64 ± 11 | 63 ± 10 | 0.316 |
Weight (mean ± SD, kg) | 85 ± 24 | 85 ± 24 | 1 |
BMI (mean ± SD, kg/m 2 ) | 29 ± 7 | 29 ± 8 | 0.517 |
Smoker | |||
Former (n,%) | 247 (18%) | 304 (19%) | 0.448 |
Current (n,%) | 228 (16%) | 267 (16%) | 0.917 |
Lung Disease (n,%) | 10 (0.7%) | 8 (0.5%) | 0.585 |
Asthma (n,%) | 114 (8%) | 134 (8%) | 0.946 |
COPD (n,%) | 73 (5%) | 100 (6%) | 0.291 |
Diabetes (n,%) | 178 (13%) | 218 (13%) | 0.578 |
Hypertension (n,%) | 506 (36%) | 616 (38%) | 0.297 |
Coronary Artery Disease (n,%) | 93 (7%) | 126 (8%) | 0.257 |
Congestive Heart Failure (n,%) | 40 (3%) | 53 (3%) | 0.579 |
Chronic Kidney Disease (n,%) | 76 (5%) | 110 (7%) | 0.139 |
Hepatic Disease (n,%) | 19 (1%) | 33 (2%) | 0.195 |
Alcohol Abuse (n,%) | 45 (3%) | 47 (3%) | 0.697 |
Current Steroid Therapy (n,%) | 46 (3%) | 61 (4%) | 0.538 |
Intraoperative variable | Before vent exchange (n = 15,481) | After vent exchange (n = 18,945) | p |
Ventilatory Parameters (case medians) | |||
PIP (mean ± SD, cmH 2 O) | 26 ± 6 | 21 ± 6 | < 0.001 |
PEEP (mean ± SD, cmH 2 O) | 2 ± 1.4 | 1.6 ± 2.6 | < 0.001 |
ΔP (mean ± SD, cmH 2 O) | 24 ± 6 | 19 ± 6 | < 0.001 |
RR (mean ± SD, breath per minute) | 11 ± 2.5 | 11 ± 3 | < 0.001 |
Vt (mean ± SD, ml) | 588 ± 139 | 562 ± 121 | < 0.001 |
Vt cc/kg PBW (mean ± SD, ml) | 9.3 ± 2.19 | 9.0 ± 1.88 | < 0.001 |
FiO 2 (mean ± SD,%) | 57.2 ± 0.17 | 51.8 ± 18 | < 0.001 |
cc/kg PBW ≤ 6 (n,%) | 90 (6%) | 104 (6%) | 1 |
cc/kg PBW ≤ 8 (n,%) | 316 (22%) | 433 (27%) | 0.009 |
Epochs of 10 minutes: | |||
PIP > 30 cmH2O | 3.5 ± 7.5 | 1.5 ± 5 | < 0.001 |
Vt > 12 cc/kg PBW | 1.8 ± 5 | 0.9 ± 4 | < 0.001 |
Colloid use (n,%) | 198 (14%) | 184 (11%) | 0.026 |
Crystalloid volume (median, 25 th ,75 th , ml) | 2000 (1200,3000) | 1900 (1000,2700) | < 0.001 |
Case Length (mean ± SD, minutes) | 220 ± 124 | 208 ± 124 | 0.005 |
Transfusion (n,%) | 79 (6%) | 76 (5%) | 0.248 |
PRBC (n,%) | 77 (5%) | 73 (5%) | 0.244 |
FFP (n,%) | 14 (1%) | 17 (1%) | 1 |
Platelets (n,%) | 7(0.5%) | 8 (0.5%) | 0.813 |