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Table 7 Factors associated with post-operative length of two weeks or less following pancreaticoduodenectomy

From: The impact of fluid intervention on complications and length of hospital stay after pancreaticoduodenectomy (Whipple’s procedure)

 

Discharge before 2 weeks

Discharge after 2 weeks

Univariate

Multivariate

Odds ratio (Confidence interval)

p value

Odds ratio (Confidence interval)

p value

(n = 62)

(n = 88)

   

Demographics

      

Male

41 (66%)

48 (55%)

1.6 (0.8–3.2)

0.155

  

Diabetes

16 (26%)

19 (22%)

1.3 (0.6–2.7)

0.548

  

COPD

2 (3%)

10 (11%)

0.3 (0.1–1.2)

0.124

  

Age ≥ 70

20 (32%)

38 (43%)

0.6 (0.3–1.2)

0.176

  

BMI ≥ 25

29 (50%)

42 (62%)

0.6 (0.3–1.3)

0.184

  

Albumin ≤ 30 g/l

12 (21%)

16 (28%)

0.7 (0.3–1.7)

0.414

  

Creatinine ≥100 (μmol/l)

6 (10%)

17 (21%)

0.4 (0.2–1.2)

0.088

0.3 (0.1–1.2)

0.085

Operative details

      

Time ≥ 8 hours

24 (39%)

25 (28%)

1.6 (0.8–3.1)

0.185

  

Blood loss ≥ 600 ml

9 (15%)

20 (23%)

0.6 (0.2–1.4)

0.202

  

Intraoperative fluid balance ≤ 3 litre

20 (32%)

13 (15%)

2.7 (1.2–6.1)

0.01*

1.7 (0.5–5.1)

0.382

High surgical volume

39 (63%)

13 (25%)

9.8 (4.5–21.4)

<0.001*

11.3 (3.8–33.8.)

<0.001*

Malignancy

49 (79%)

76 (86%)

0.6 (0.3–1.4)

0.235

  

Post–operative details

      

Complication

15 (24%)

71 (80%)

0.1 (0.0–0.2)

<0.001*

0.1 (0.1–0.4)

<0.001*

Day 1 fluid balance ≤ 1 litre

35 (57%)

27 (31%)

2.9 (1.5–5.8)

0.002*

2.9 (1.1–6.6)

0.037*

Day 2 fluid balance ≤ 0.2 litre

33 (53%)

37 (31%)

2.6 (1.3–5.0)

0.006*

0.8 (0.3–2.5)

0.752

Day 3 fluid balance ≤ 0.2 litre

36 (58%)

32 (36%)

2.4 (1.2–4.7)

0.009*

2.5 (1.0–6.6)

0.056

  1. Data are presented as number (%) or median (range).
  2. COPD – Chronic obstructive pulmonary disease. BMI – body mass index; Missing: BMI – 24, Albumin -35, Creatinine 10, Estimate blood loss - 3 *p ≤ 0.05; Chi-Square/Fisher’s exact test.