Table 6 Factors associated with overall complications following pancreaticoduodenectomy
Complications | No complications | Univariate | Multivariate | |||
|---|---|---|---|---|---|---|
(n = 86) | (n = 64) | Odds ratio (Confidence interval) | p value | Odds ratio (Confidence interval) | p value | |
Demographics | ||||||
BMI ≥ 25 | 43 (62%) | 28 (49%) | 1.7 (0.8–3.5) | 0.137 | ||
Albumin ≤ 30 g/l | 19 (34%) | 9 (15%) | 2.9 (1.2–7.40 | 0.020* | 1.6 (0.6–4.6) | 0.389 |
Creatinine >100 (μmol/l) | 17 (22%) | 6 (10%) | 2.6 (1.0–7.1) | 0.055 | 3.9 (1.1–13.4) | 0.033* |
Operative details | ||||||
Time ≥ 8 hours | 24 (28%) | 25 (39%) | 0.6 (0.3–1.2) | 0.150 | ||
Blood loss ≥ 600 ml | 15 (18%) | 14 (22%) | 0.8 (0.4–1.7) | 0.510 | ||
Intraoperative fluid balance ≤ 3 litre | 29 (34%) | 32 (50%) | 0.3 (0.1–0.7) | 0.006* | 0.6 (0.2–1.7) | 0.367 |
High surgical volume | 12 (14%) | 21 (33%) | 0.2 (0.1–0.4) | <0.001* | 0.2 (0.1–0.5) | 0.001* |
Post–operative details | ||||||
Day 1 fluid balance ≤ 1 litre | 26 (30%) | 36 (56%) | 0.4 (0.2–0.7) | 0.001* | 0.2 (0.1–0.6) | 0.001* |
Day 2 fluid balance ≤ 0.2 litre | 28 (33%) | 32 (50%) | 0.5 (0.3–0.9) | 0.031* | 0.8 (0.3–2.1) | 0.685 |
Day 3 fluid balance ≤ 0.2 litre | 36 (42%) | 32 (50%) | 0.7 (0.4–1.4) | 0.32 | ||