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Table 4 Operative and pathology of patients undergoing pancreaticoduodenal resection with and without complications

From: The impact of fluid intervention on complications and length of hospital stay after pancreaticoduodenectomy (Whipple’s procedure)

 

Overall

Complications

No complications

p value

(n = 150)

(n = 86)

(n = 64)

Malignancy

125 (83%)

74 (86%)

51 (80%)

0.301

Epidural anesthesia

84 (57%)

45 (53%)

39 (62%)

0.276

Intrathecal morphine

20 (13%)

8 (9%)

12 (19%)

0.092

Pylorus preserving

63 (42%)

40 (47%)

23 (36%)

0.194

Surgeons with higher surgical volumes*

   

0.001*

   Surgeon 1

52 (35%)

17 (20%)

35 (55%)

 

   Surgeon 2

29 (19%)

19 (22%)

10 (16%)

 

   Surgeon 3

13 (9%)

8 (9%)

5 (8%)

 

   Surgeon 4

9 (6%)

6 (7%)

3 (5%)

 

   Surgeon 5

20 (13%)

15 (17%)

5 (8%)

 

Other

27 (18%)

21 (24%)

6 (9%)

 

Estimated blood loss (ml)

350 (100–2500)

350 (100–1900)

400 (200–2500)

0.027*

Blood transfusions intraoperative

28 (19%)

16 (19%)

12 (19%)

0.982

Intraoperative fluids (l)

5.0 (1.0–12.3)

5.4 (2.5–12.3)

5.0 (1.0–10.6)

0.047*

Fluid balance (l)

4.5 (0.2–12.0)

4.7 (1.6–12.0)

4.1 (0.2–9.4)

0.044*

Inotropes and vasoconstrictors

   

0.89

Total use

90 (60%)

55 (64%)

35 (55%)

Norepinephrine

8 (5%)

5 (6%)

3 (5%)

Metaraminol

70 (47%)

39 (45%)

31 (48%)

Ephedrine

15 (10%)

9 (10%)

8 (13%)

Dopamine

5 (3%)

3 (3%)

2 (3%)

Operative time (hours)

7.0 (3–15.8)

6.6 (3–15.8)

7.2 (3–12)

0.056

  1. *Defined as greater than 10 pancreatic resections per annum.