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Table 1 MALDI-TOF MS identification of differentially expressed protein

From: Proteomic profiling of the phosphoproteins in the rat thalamus, hippocampus and frontal lobe after propofol anesthesia

Spota

Protein name

Uniprot accession

Theoretical Mr (kDa)b

Total scorec

Queries Machedd

P/Ce

1

Keratin 18

Q5BJY9

47.76

72

100%

↓

2

Gelsolin

Q68FP1

86.07

24

99.96%

↑

3

Hemoglobin

P02091

15.85

30

99.95%

↑

4

Macrophage-capping protein

Q6AYC4

28.80

148

100%

↓

6

Tubulin beta-2C chain

Q6P9T8

49.80

43

99.96%

↓

7

Apolipoprotein E

P02650

35.75

29

99.92%

↓

9

Glutathione peroxidase 3

P23764

25.27

87

100%

↑

10

Betaine-homocysteine S-methyltransferase 1

O96171

44.98

62

100%

↑

11

SET domain-containing protein 6

D3ZSK5

54.55

76

100%

↑

12

Cytochrome c oxidase subunit 5A

P11240

16.20

29

99.91%

↑

13

Delta-aminolevulinic acid dehydratase

P06214

36.03

33

99.95%

↓

15

40S ribosomal protein SA

P38983

42.91

150

100%

↓

16

Thioredoxin-like protein 1

Q920J4

32.25

156

100%

↓

18

ATP synthase subunit alpha

P31399

59.75

23

99.95%

↓

19

Metastasis-associated protein MTA1

Q62599

79.41

52

100%

↓

21

Actin, aortic smooth muscle

P62738

42.01

62

100%

↓

  1. aThe numbers indicate the spot positions in 2D gel as shown in Figure 1.
  2. bCaculated from the database entry without any processing.
  3. cBy MALDI-TOF MS analysis.
  4. dBy MALDI-TOF MS analysis.
  5. eP/C propofol group compared with control group.