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Table 3 Femoral venous carbon dioxide partial pressure (PCO 2 ) of malignant hyperthermia susceptible (MHS) and non-susceptible (MHN) pigs following succinylcholine or halothane or succinylcholine and halothane application

From: The effect of succinylcholine on malignant hyperthermia events in susceptible swine

Diagnose

Femoral venous PCO2[mmHg] t = 0 min

t = 15 min

t = 30 min

t = 45 min

MHSSCh (n = 9)

51 [45–54]

52 49–56]

78 [67–93]*#

79 [72–105]*#

MHNSCh (n = 10)

50 [43–55]

49 [44–54]

51 [45–56]

49 [43–56]

MHSHalothane (n = 6)

59 [46–67]

55 [45–60]

71 [58–84]*

138 [98–152]*#

MHNHalothane (n = 10)

50 [44–58]

52 [44–57]

54 [44–58]

54 [44–60]

MHSHalothane+SCh (n = 12)

51 [47–56]

57 [53–64]

151 [110–192]*#

199+

MHNHalothane+SCh (n = 10)

51 [44–53]

49 [44–52]

50 [47–57]

51 [47–61]

  1. t = 0 minutes: Baseline values; t = 15 minutes: Application of 4 mg/kg succinylcholine or 0.5 vol% halothane or both; t = 30 minutes: Application of 4 mg/kg succinylcholine or 1 vol% halothane or both.
  2. SCh = succinylcholine.
  3. Data as median and interquartile range.
  4. *significant changes from baseline values; #significant differences between MHS and MHN; p < 0.05. +: data from only one MHS animal.