Table 5 Multivariate Cox regression of laryngospasm based on period of anesthesia (n = 42,055)

Age (ref= > 6)

1^a 0.08

1^a 0.004

1^a 0.002

1-6

_

1.4 (0.57, 3.6)^a

3.4 (1.5, 7.8)^b

8.5 (1.8, 40.3)^b

< 1

3.7 (1.2, 11.3)^b

3.4 (0.99, 11.6)^a

27.4 (5.2, 143.2)^c

Respiratory disease (ref = no)

1^a 0.02

s

URI

1.7 (0.78, 3.7)^a

_

_

_

Pulmonary disease

3.1 (1.5, 6.4)^b

ASA classification (ref = 1)

1^a 0.23

2

0.82 (0.47, 1.4)^a

_

_

_

3

0.39 (0.12, 1.3)^a

Airway device (ref = ETT-C)

1^a < 0.001

Jet ventilation-C

_

Facemask-A

18.1 (6.4, 51.4)^b

LMA-A

12.5 (4.6, 33.9)^b

Intubating agent (ref = NDMR)

1^a < 0.001

1^a 0.67

Succinylcholine

_

13.5 (3.9, 46.3)^b

1.4 (0.28, 6.9)^a

_

Sevoflurane

1.9 (0.18, 19.5)^a

2.8 (0.6, 13.0)^a

Inhalation agent (ref = sevoflurane)

1^a < 0.001

Isoflurane

0.75 (0.38, 1.5)^a

_

_

_

Halothane

1.6 (0.37, 6.5)^a

Desflurane

11.0 (5.1, 23.9)^b