In vivo study of the effects of exogenous hydrogen sulfide on lung mitochondria in acute lung injury in rats

BMC Anesthesiology

Table 1 Effects of NaHS on lung mitochondrial and cytosol Cyt-c protein expression in acute lung injury rats ( $\bar{x}$ ±s, n = 8)

Group	Cyt-c (mitochondria) (Grayscale scan value)	Cyt-c (cytosol) (Grayscale scan value)	β-actin (Grayscale scan value)
control group	178.51	96.992	171.47
LPS injury group	41.177**	293.45**	183.66
L	62.846^#	226.91^#	182.52
M	88.344^##	203.38^##	196.02
H	115.27^##	111.84^##	169.28

**P < 0.01,compared to the control group; ^# P < 0.05, ^## P < 0.01, compared to the LPS injury group; L:LPS + low-dose NaHS group; M:LPS + middle-dose NaHS group;H: LPS + high-dose NaHS group.
The lung mitochondrial Cyt-c protein expression was significantly decreased in the LPS injury group compared to the control group (P < 0.01). In three LPS + NaHS groups, lung mitochondrial Cyt-c protein expression was markedly increased compared to the LPS injury group (P < 0.05 or P < 0.01). The cytosol Cyt-c protein expression was significantly increased in the LPS injury group compared to the control group (P < 0.01). In three LPS + NaHS groups, cytosol Cyt-c protein expression was markedly decreased compared to the LPS injury group (P < 0.05 or P < 0.01).

ISSN: 1471-2253