Table 4 Matching, baseline and outcome variables for patients receiving (FBNc group) or not (comparator group) FBNc
Variables | FBNc N = 38 | Control N = 38 | P value |
|---|---|---|---|
Age (years) | 62 [55, 68] | 62 [57, 73] | NS |
SOFA | 6 [4, 8] | 5.5 [4, 8] | NS |
Gender (males) | 26 (68.4) | 31 (81.5) | NS |
Haemorrhage occurring outside the OR or ICU | 10 (26.3) | 10 (26.3) | NS |
Diagnoses | |||
Cardiac surgery | 21 (55.3) | 21 (55.3) | |
Liver transplantation | 7 (18.4) | 7 (18.4) | |
Gastrointestinal bleeding | 10 (26.6) | 10 (26.6) | NS |
Variables at beginning of bleeding | |||
pH | 7.30 [7.28, 7.33] | 7.31 [7.26, 7.37] | NS |
Base excess (mEq/L) | -4.7 [-8.0, -3.0] | -4.0 [-6.0, 0.4] | NS |
Creatinine (mg/dL) | 0.8 [0.7, 1.3] | 0.9 [0.7, 1.4] | NS |
Leucocytes (x 109/L) | 7.1 [4.7,11.7] | 9.7 [7.3, 15.0] | 0.04 |
Platelets (x 109/L) | 112 [72, 173] | 98 [63, 144] | NS |
Haemoglobin (g/L) | 84.5 [72.0, 108.0] | 70.0 [64.0, 75.0] | 0.00 |
Prothrombin time (s) | 18.0 [13.0, 28.0] | 18.0 [14.0, 21.0] | NS |
Thromboplastin time (s) | 43.5 [32.4, 63.8] | 47.7 [36.2, 59.2] | NS |
Fibrinogen (g/L) | 1.7 [0.9, 2.3] | 2.0 [1.5, 3.3] | 0.04 |
INR | 1.6 [1.2, 2.5] | 1.5 [1.2, 1.8] | NS |
Outcome variables | |||
In-hospital mortality | 13 (34.2) | 10 (26.3) | NS |
Length of hospital stay (days)* | 15 [7, 32] | 22 [14, 29] | NS |
PRBC (units) | 8 [5, 12] | 6 [5, 12] | NS |
FFP (units) | 2 [0, 5] | 3 [0, 5] | NS |
Platelet (pools) | 1 [0, 2] | 2 [1, 3] | NS |
Total transfusion (units) | 11 [6, 20] | 10 [6, 16] | NS |