Table 1 Characteristics of both cohorts of patients, receiving (FBNc group) or not (comparator group) FBNc
Variables | FBNc N = 71 | Comparator N = 72 | P value |
|---|---|---|---|
Age (years) | 57 [44, 66] | 63 [53, 72] | 0.02 |
SOFA | 7 [4, 10] | 5 [3, 8] | 0.03 |
Gender (males) | 46 (65) | 55 (76) | NS |
Haemorrhage occurring outside the OR or ICU | 25 (35.2) | 24 (33.3) | NS |
Diagnoses | |||
Cardiac Surgery | 37 (51.4) | 35 (49.3) | NS |
Liver Transplantation | 11 (15.3) | 11 (15.5) | |
Gastrointestinal Bleeding | 16 (22.2) | 15 (21.1) | |
Other | 8 (11.1) | 10 (14.1) | |
Variables at beginning of the bleeding | |||
pH | 7.30 [7.29, 7.32] | 7.31 [7.26, 7.3] | NS |
Base excess (mEq/L) | -4.3 [-7.3, -3.0] | -4.0 [-6.2, 0.3] | 0.04 |
Creatinine (mg/dl) | 0.9 [0.7, 1.3] | 0.9 [0.7, 1.6] | NS |
Leukocytes (x 109/L) | 7.4 [4.7, 12.9] | 10.3 [8.1,14.6] | 0.04 |
Platelets (x 109/L) | 93 [49, 150] | 100 [63, 144] | NS |
Haemoglobin (g/L) | 85.0 [71.5, 103.0] | 70.0 [64.0, 75.0] | 0.001 |
Prothrombin time (s) | 19.2 [14.1, 31.6] | 16.7 [14.7, 20.3] | NS |
Thromboplastin time (s) | 46.1 [34.1, 97.3] | 43.5 [34.0, 55.5] | NS |
Fibrinogen (g/L) | 1.3 [0.9, 2.2] | 2.0 [1.4, 3.1] | 0.001 |
INR | 1.7 [1.2, 2.8] | 1.4 [1.2, 1.7] | 0.01 |
Outcome variables | |||
In-hospital mortality | 29 (40.8) | 20 (27.8) | NS |
Length of hospital stay (days)* | 14 [7, 30] | 23 [17, 33] | 0.01 |
PRBC (units) | 9 [5, 16] | 6 [4,10] | 0.001 |
FFP (units) | 2 [0, 6] | 3 [0, 6] | NS |
Platelet (pools) | 2 [1, 3] | 1 [0, 2] | 0.001 |
Total transfusion (units) | 15 [8, 25] | 10 [6, 18] | 0.02 |