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Table 1 Hemodynamic parameters, central venous blood gases and microcirculatory variables

From: Non-invasive detection of hypovolemia or fluid responsiveness in spontaneously breathing subjects

 

Baseline

−20 mmHg LBNP

−40 mmHg LBNP

RRI (msec)

859 ± 159

844 ± 144

739 ± 115##§§

SAP (mmHg)

130 ± 17

126 ± 15

123 ± 11##§

MAP (mmHg)

83 ± 13

84 ± 10

87 ± 8

CVP (mmHg)

7.2 ± 2.0

3.7 ± 2.0**

2.6 ± 2.0##

PP (mmHg)

65 ± 10

58 ± 10

50 ± 7

SV (ml)

79 ± 12

63 ± 12**

50 ± 8##§§

pH

7.38 ± 0.02

7.39 ± 0.03

7.39 ± 0.04#

pCO2 (mmHg)

45 ± 3

43 ± 4

43 ± 5#

pO2 (mmHg)

42 ± 5

37 ± 4*

36 ± 4##

ScvO2 (%)

76 ± 6

70 ± 7*

67 ± 9##

Hb (g/dl)

13.7 ± 0.8

14 ± 0.8**

14.5 ± 0.9##§§

RBCV (microm/s)

1035 ± 67

792 ± 153**

696 ± 156##§

MPCL (microm)

2696 ± 593

2194 ± 567**

1973 ± 512##

PRPV (%)

99.7 ± 1.5

90.4 ± 13*

87.8 ± 13.9##

MFI

3.0 ± 0

2.8 ± 0.4 *

2.7 ± 0.4 #

  1. Hemodynamic data are calculated from the whole 3 minute recordings at 6/min patterned breathing at baseline and during mild (−20 mmHg LBNP) and moderate (−40 mmHg LBNP) central hypovolemia and are given as mean ± SD.
  2. *baseline vs. -20 mmHg, p < 0.05.
  3. **baseline vs. -20 mmHg, p < 0.001.
  4. #baseline vs. -40 mmHg, p < 0.05.
  5. ##baseline vs. -40 mmHg, p < 0.001.
  6. §-20 vs −40 mmHg, p < 0.05.
  7. §§-20 vs −40 mmHg, p < 0.001.