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Table 1 Patient characteristics by initial therapy

From: Candidemia in the critically ill: initial therapy and outcome in mechanically ventilated patients

Characteristic

Echinocandin

Fluconazole

P

(n = 315)

(n = 374)

Male

168 (53%)

198 (53%)

.94

Age

58 ± 17

56 ± 21

.17

Immunosuppressive therapy within 30 days

189 (60%)

155 (41%)

<.001

 Corticosteroids

184 (58%)

153 (41%)

<.001

Nonsteroid immunosuppressive therapy

43 (14%)

25 (7%)

.003

Renal injury (serum creatinine > 2 mg/dL or dialysis)

146 (46%)

124 (33%)

<.001

 Dialysis (chronic or acute)

101 (32%)

77 (21%)

<.001

Any malignancy

49 (16%)

61 (16%)

.83

 Hematologic malignancy

17 (5%)

8 (2%)

.025

 Solid tumor

34 (11%)

55 (15%)

.14

Neutropenia within in the preceding 30 days

20 (6%)

2 (1%)

<.001

Diabetes mellitus

139 (44%)

134 (36%)

.029

Abnormal hepatic function

123 (39%)

120 (32%)

.066

 Transaminitis

84 (27%)

81 (22%)

.13

 Hyperbilirubinemia

87 (28%)

79 (21%)

.050

Solid organ transplant

31 (10%)

16 (4%)

.004

HIV seropositive

6 (2%)

5 (1%)

.56

Surgical patient

119 (38%)

164 (44%)

.12

  1. Values are n (%) or mean ± SD.