Figure 1From: Xylazine-induced reduction of tissue sensitivity to insulin leads to acute hyperglycemia in diabetic and normoglycemic monkeys Intravenous glucose tolerance test (ivGTT) in normoglycemic and insulin-dependent diabetic cynomolgus monkeys (Table 1 ). Plasma glucose and insulin levels were measured at the scheduled time points in normoglycemic (panel A, n = 5) and insulin-dependent diabetic (panel B, n = 5) monkeys. Panel C shows the glucose AUCs of the ivGTTs for the nomorglycemic (blank bar) and diabetic (strip bar) monkeys. Panel D shows the insulin AUCs of the ivGTTs for the normoglycemic (blank bar) and diabetic (strip bar) monkeys. *, p < 0.05; **, p < 0.01, ***, p < 0.001; vs. the level at time zero or vs. the normoglycemic group.Back to article page