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Table 2 Results of the control group with the 3 study groups

From: The effects of levosimendan and dobutamine in experimental bupivacaine-induced cardiotoxicity

Study groups

Control

Levosimendan

Dobutamine

Dobutamine+Levosimendan

Initial QRS > 20% (s)

162 (101-342)

173 (103-403)

153 (105-410)

159 (90-432)

Initial arrhythmia (s)

203 (129-549)

455 (153-850)

448 (249-1367)

310 (97-567)

Heart rate < 50% (s)

345 (214-583)

903* (301-1848)

984 *(672-2814)

1705 †* (1039-3009)

Heart rate < %75 (s)

538 (353-961)

1198* (358-7014)

1542 * (895-4092

3152 †* (1747-6519

Mean arterial pressure < %50 (s)

399 (245-665)

1005* (243-1592)

685* (514-1992)

1544 †* (874-3003)

Mean arterial pressure < %75 (s)

504 (381-814)

1204* (298-6028)

1009* (698-4013)

2982 †* (1542-6897)

Cardiac arrest time (s)

703 (403-1049)

1385* (412-6552)

1789 * (944-4742)

3357 †* (1825-7200)

Total Bupivacaine dose (μg)

8.48 (5.03-13.11)

17.62 * (5.15-90.0)

22.36 * (11.80-59.20)

41.90 †* (22.80-90.0)

  1. Data is given as median with minimum and maximum values.
  2. *p < 0.05 compared to the control group, †p < 0.008 for pairwise comparison of all 4 groups.