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Table 2 Results of the control group with the 3 study groups

From: The effects of levosimendan and dobutamine in experimental bupivacaine-induced cardiotoxicity

Study groups Control Levosimendan Dobutamine Dobutamine+Levosimendan
Initial QRS > 20% (s) 162 (101-342) 173 (103-403) 153 (105-410) 159 (90-432)
Initial arrhythmia (s) 203 (129-549) 455 (153-850) 448 (249-1367) 310 (97-567)
Heart rate < 50% (s) 345 (214-583) 903* (301-1848) 984 *(672-2814) 1705 †* (1039-3009)
Heart rate < %75 (s) 538 (353-961) 1198* (358-7014) 1542 * (895-4092 3152 †* (1747-6519
Mean arterial pressure < %50 (s) 399 (245-665) 1005* (243-1592) 685* (514-1992) 1544 †* (874-3003)
Mean arterial pressure < %75 (s) 504 (381-814) 1204* (298-6028) 1009* (698-4013) 2982 †* (1542-6897)
Cardiac arrest time (s) 703 (403-1049) 1385* (412-6552) 1789 * (944-4742) 3357 †* (1825-7200)
Total Bupivacaine dose (μg) 8.48 (5.03-13.11) 17.62 * (5.15-90.0) 22.36 * (11.80-59.20) 41.90 †* (22.80-90.0)
  1. Data is given as median with minimum and maximum values.
  2. *p < 0.05 compared to the control group, †p < 0.008 for pairwise comparison of all 4 groups.