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Table 3 Microcirculatory data

From: The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome

   Bsln T1a (+24 h) T1b (+48 h) T1c (+72 h) T2 (6 h after aPC stop)
MFI (AU) aPC 1.7 (1.5–2.3) 2.9 (2.5–3) ## 3 (2.5–3) # 2.9 (2.7–3) #* 3 (2.9–3) ###**
  no-aPC 2.7 (1.5–3) 2.3 (2–3) 2.6 (1.7–2.9) 2.5 (2–2.6) 1.7 (1.6–2.8)
MFIs (AU) aPC 1.5 (1–2.3) 3 (2.8–3) ## 3 (2.5–3) # 3 (2.7–3) ## 3 (2.8–3) ## *
  no-aPC 2.7 (2–3) 2.8 (2–3) 2.7 (2.1–3) 2.8 (2.4–3) 2 (1.6–3)
TVD (mm/mm2) aPC 11.1 (9.8–15) 14.5 (11.9–16) 14.3 (12–16.4) 14.1 (12.5–17.3) 16 (13.5–20) ###
  no-aPC 14.9 (11.4–19.4) 16.2 (11.5–22.5) 14.2 (10–20.4) 16.6 (11.9–20.3) 15.4 (11.3–18.2)
PVD (mm/mm2) aPC 5.1 (3.2–7.7) * 10.7 (7–12.8) 7.4 (4.1–11.6) 11 (10–13.2) ## 11.6 (9.4–14.7) ## *
  no-aPC 9.2 (5.9–17.8) 9.5 (5.1–20.6) 8.3 (7.1–15) 9 (6–17.9) 8.5 (4.3–10.6)
PPV (%) aPC 46 (32–55) 73 (59–83) 57 (37–82) 84 (66–93) ## 69 (65–85) *
  no-aPC 72 (43–94) 60 (45–89) 71 (54–90) 53 (41–88) 56 (32–72)
De Backer score (n/mm) aPC 7.9 (5–9.7) 10.4 (6.2–11.1) 8.7 (5–11.3) 10.7 (7.8–13.8) 11.5 (8.4–14) *
  no-aPC 10.5 (6.4–13.4) 8.2 (5.8–12) 8.9 (5.8–11.6) 8.3 (7.2–12.3) 7.3 (5.9–11.3)
HI (AU) aPC 0.5 (0.13–1.5) 0.25 (0–0.5) 0 (0–0.42) 0 (0–0.5) 0 (0–0) # *
  no-aPC 0.07 (0–0.41) 0.07 (0–0.57) 0.07 (0–0.58) 0 (0–0.42) 0.5 (0–1.75)
PBR (μm) aPC 2.69 (2.11–3.11) 2.53 (2.36–2.73) 2.61 (2.46–2.79) 2.62 (2.33–2.81) 2.52 (2.40–2.65)
  no-aPC 2.94 (2.65–3.08) 2.60 (2.54–2.84) 2.76 (2.56–2.84) 2.63 (2.43–3.00) 2.65 (2.61–2.73)
  1. #p < 0.05, vs. T0 in the aPC-group (## p < 0.01; ### p < 0.0001).
  2. *p < 0.05, aPC group vs. no-aPC group at the same time point (**p < 0.01).