From: The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome
 |  | Bsln | T1a (+24 h) | T1b (+48 h) | T1c (+72 h) | T2 (6 h after aPC stop) |
---|---|---|---|---|---|---|
MFI (AU) | aPC | 1.7 (1.5–2.3) | 2.9 (2.5–3) ## | 3 (2.5–3) # | 2.9 (2.7–3) #* | 3 (2.9–3) ###** |
 | no-aPC | 2.7 (1.5–3) | 2.3 (2–3) | 2.6 (1.7–2.9) | 2.5 (2–2.6) | 1.7 (1.6–2.8) |
MFIs (AU) | aPC | 1.5 (1–2.3) | 3 (2.8–3) ## | 3 (2.5–3) # | 3 (2.7–3) ## | 3 (2.8–3) ## * |
 | no-aPC | 2.7 (2–3) | 2.8 (2–3) | 2.7 (2.1–3) | 2.8 (2.4–3) | 2 (1.6–3) |
TVD (mm/mm2) | aPC | 11.1 (9.8–15) | 14.5 (11.9–16) | 14.3 (12–16.4) | 14.1 (12.5–17.3) | 16 (13.5–20) ### |
 | no-aPC | 14.9 (11.4–19.4) | 16.2 (11.5–22.5) | 14.2 (10–20.4) | 16.6 (11.9–20.3) | 15.4 (11.3–18.2) |
PVD (mm/mm2) | aPC | 5.1 (3.2–7.7) * | 10.7 (7–12.8) | 7.4 (4.1–11.6) | 11 (10–13.2) ## | 11.6 (9.4–14.7) ## * |
 | no-aPC | 9.2 (5.9–17.8) | 9.5 (5.1–20.6) | 8.3 (7.1–15) | 9 (6–17.9) | 8.5 (4.3–10.6) |
PPV (%) | aPC | 46 (32–55) | 73 (59–83) | 57 (37–82) | 84 (66–93) ## | 69 (65–85) * |
 | no-aPC | 72 (43–94) | 60 (45–89) | 71 (54–90) | 53 (41–88) | 56 (32–72) |
De Backer score (n/mm) | aPC | 7.9 (5–9.7) | 10.4 (6.2–11.1) | 8.7 (5–11.3) | 10.7 (7.8–13.8) | 11.5 (8.4–14) * |
 | no-aPC | 10.5 (6.4–13.4) | 8.2 (5.8–12) | 8.9 (5.8–11.6) | 8.3 (7.2–12.3) | 7.3 (5.9–11.3) |
HI (AU) | aPC | 0.5 (0.13–1.5) | 0.25 (0–0.5) | 0 (0–0.42) | 0 (0–0.5) | 0 (0–0) # * |
 | no-aPC | 0.07 (0–0.41) | 0.07 (0–0.57) | 0.07 (0–0.58) | 0 (0–0.42) | 0.5 (0–1.75) |
PBR (μm) | aPC | 2.69 (2.11–3.11) | 2.53 (2.36–2.73) | 2.61 (2.46–2.79) | 2.62 (2.33–2.81) | 2.52 (2.40–2.65) |
 | no-aPC | 2.94 (2.65–3.08) | 2.60 (2.54–2.84) | 2.76 (2.56–2.84) | 2.63 (2.43–3.00) | 2.65 (2.61–2.73) |