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Table 3 Microcirculatory data

From: The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome

  

Bsln

T1a (+24 h)

T1b (+48 h)

T1c (+72 h)

T2 (6 h after aPC stop)

MFI (AU)

aPC

1.7 (1.5–2.3)

2.9 (2.5–3) ##

3 (2.5–3) #

2.9 (2.7–3) #*

3 (2.9–3) ###**

 

no-aPC

2.7 (1.5–3)

2.3 (2–3)

2.6 (1.7–2.9)

2.5 (2–2.6)

1.7 (1.6–2.8)

MFIs (AU)

aPC

1.5 (1–2.3)

3 (2.8–3) ##

3 (2.5–3) #

3 (2.7–3) ##

3 (2.8–3) ## *

 

no-aPC

2.7 (2–3)

2.8 (2–3)

2.7 (2.1–3)

2.8 (2.4–3)

2 (1.6–3)

TVD (mm/mm2)

aPC

11.1 (9.8–15)

14.5 (11.9–16)

14.3 (12–16.4)

14.1 (12.5–17.3)

16 (13.5–20) ###

 

no-aPC

14.9 (11.4–19.4)

16.2 (11.5–22.5)

14.2 (10–20.4)

16.6 (11.9–20.3)

15.4 (11.3–18.2)

PVD (mm/mm2)

aPC

5.1 (3.2–7.7) *

10.7 (7–12.8)

7.4 (4.1–11.6)

11 (10–13.2) ##

11.6 (9.4–14.7) ## *

 

no-aPC

9.2 (5.9–17.8)

9.5 (5.1–20.6)

8.3 (7.1–15)

9 (6–17.9)

8.5 (4.3–10.6)

PPV (%)

aPC

46 (32–55)

73 (59–83)

57 (37–82)

84 (66–93) ##

69 (65–85) *

 

no-aPC

72 (43–94)

60 (45–89)

71 (54–90)

53 (41–88)

56 (32–72)

De Backer score (n/mm)

aPC

7.9 (5–9.7)

10.4 (6.2–11.1)

8.7 (5–11.3)

10.7 (7.8–13.8)

11.5 (8.4–14) *

 

no-aPC

10.5 (6.4–13.4)

8.2 (5.8–12)

8.9 (5.8–11.6)

8.3 (7.2–12.3)

7.3 (5.9–11.3)

HI (AU)

aPC

0.5 (0.13–1.5)

0.25 (0–0.5)

0 (0–0.42)

0 (0–0.5)

0 (0–0) # *

 

no-aPC

0.07 (0–0.41)

0.07 (0–0.57)

0.07 (0–0.58)

0 (0–0.42)

0.5 (0–1.75)

PBR (μm)

aPC

2.69 (2.11–3.11)

2.53 (2.36–2.73)

2.61 (2.46–2.79)

2.62 (2.33–2.81)

2.52 (2.40–2.65)

 

no-aPC

2.94 (2.65–3.08)

2.60 (2.54–2.84)

2.76 (2.56–2.84)

2.63 (2.43–3.00)

2.65 (2.61–2.73)

  1. #p < 0.05, vs. T0 in the aPC-group (## p < 0.01; ### p < 0.0001).
  2. *p < 0.05, aPC group vs. no-aPC group at the same time point (**p < 0.01).