Evaluation of suspected malignant hyperthermia events during anesthesia

BMC Anesthesiology

Table 2 Applied trigger agents and clinical presentations of malignant hyperthermia suspected events

No	IVCT	Trigger agents	Masseterspasm	Dantrolene application	Cardiac arrhythmia	Max. end-tidal CO₂[mmHg]	Max. temperature	Max. Creatine kinase [U/L]
1	MHS	Isoflurane + SCh	Unknown	1 × 200 mg	Sinus tachycardia	48 mmHg	38.8°C	10.514
2	MHS	Isoflurane + SCh	Yes	1 × 240 mg	Tachyarrhythmia	54 mmHg	36.1°C	> 10.000
3	MHS	Sevoflurane + SCh	Yes	No	Sinus tachycardia	Unknown	Unknown	51.557
4	MHS	Sevoflurane + SCh	Unknown	2 × 200 mg	Sinus tachycardia	62 mmHg	Unknown	23.700
5	MHS	Desflurane + SCh	Unknown	1 × 220 mg	Tachyarrhythmia	56 mmHg	37.6°C	≈ 80.000
6	MHS	Sevoflurane	No	1 × 200 mg	No	85 mmHg	37.5°C	38.762
7	MHS	Isoflurane + SCh	Unknown	No	Unknown	Unknown	Unknown	16.412
8	MHEh	SCh	Yes	1 × 200 mg	Unknown	39 mmHg	Unknown	119.150
9	MHEh	SCh	Yes	Unknown	No	36 mmHg	Unknown	162
10	MHEh	SCh	Yes	No	Unknown	Unknown	Unknown	2.234
11	MHEh	Halothane + SCh	Yes	Unknown	Tachyarrhythmia	Unknown	Unknown	Low
12	MHN	SCh	Yes	No	Tachyarrhythmia	Unknown	Unknown	132
13	MHN	Isoflurane	Yes	No	Unknown	54 mmHg	Unknown	4.100
14	MHN	SCh	Yes	No	Unknown	Unknown	Unknown	24.732
15	MHN	Desflurane	No	1 × 180 mg	Tachyarrhythmia	72 mmHg	Unknown	Unknown
16	MHN	SCh	Yes	No	Unknown	Unknown	Unknown	Unknown
17	MHN	Desflurane	No	No	Unknown	Unknown	38,5°C	Unknown
18	MHN	Isoflurane + SCh	Yes	No	Unknown	41 mmHg	Unknown	5.174
19	MHN	Enflurane + SCh	Yes	No	Unknown	75 mmHg	Unknown	4.820

IVCT In vitro contracture test, MHS Malignant hyperthermia susceptible, MHN malignant hyperthermia non-susceptible, MHEh Malignant hyperthermia equivocal to halothane, SCh Succinylcholine, CO ₂ Carbon dioxide.

ISSN: 1471-2253