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Table 4 Diagnostic accuracy of CRP, DD and PCT for sepsis diagnosis according to the LCA gold standard

From: A latent class approach for sepsis diagnosis supports use of procalcitonin in the emergency room for diagnosis of severe sepsis

Operating characteristics CRP DD PCT
(12 mg/dl) (1848 ng/ml) (2.06 ng/ml)
AUC - ROC 0.71 0.73 0.95
(0.68 – 0.74) (0.69 – 0.76) (0.93 – 0.96)
Sensitivity 64.17% 65.24% 91.44%
(0.57 – 0.71) (0.58 – 0.72) (0.86 – 0.95)
Specificity 64.47% 65.23% 91.35%
(0.60 – 0.68) (0.61 – 0.69) (0.89 – 0.94)
LR + 1.81 1.88 10.81
(1.54 – 2.11) (1.60 – 2.19) (8.15 – 14.35)
LR - 0.56 0.53 0.09
(0.45 – 0.68) (0.43 – 0.66) (0.06 – 0.15)
  1. Values between parentheses are cut-off points and 95% Confidence Interval, respectively. LR, likelihood ratio.