Table 1 Clinical characteristics at admission according to the groups defined by the expert consensus
Clinical | Sepsis | Infected without sepsis | No infected | P* value |
|---|---|---|---|---|
characteristics | n = 505 | n = 112 | n = 148 | |
SOFA score | 3 (2–4, 505) | 1.5 (1–2, 112) | 2 (1–4, 148) | 0.001 |
APACHE II score | 10 (6–16, 505) | 6 (2–10, 112) | 9 (5–14, 148) | 0.001 |
Temperature (°C) | 37 (36.5 - 38, 472) | 36.9 (36.5 - 37, 102) | 37 (36.5 - 37, 131) | 0.064 |
Heart rate | 100 (87–115, 493) | 83.5 (74–90, 106) | 90 (79–108, 146) | 0.001 |
Respiratory rate | 22 (20–28, 121) | 18 (16–20, 15) | 24 (20–36, 27) | 0.001 |
MAP | 104 (91–120, 493) | 113 (103–126, 106) | 108 (95–130, 146) | 0.001 |
WBC (cells/mm3) | 12900 (8900–17900, 500) | 9450 (7500–11400, 112) | 10400 (8000–13100, 147) | 0.001 |
Neutrophils (%) | 82 (74–89, 500) | 71 (60–81, 111) | 77 (66–86, 147) | 0.001 |
Hemoglobin (g/dl) | 12 (11–14, 500) | 12 (11–14, 111) | 13 (11–15, 147) | 0.069 |
Creatinin (mg/dl) | 1 (0.8 – 1.9, 500) | 0.9 (0.8 – 1.3, 110) | 0.9 (0.8 – 1.5, 146) | 0.035 |
Lactic Acid (mmol/L) | 1.9 (1.2 – 2.9, 494) | 1.4 (1.0 – 1.8, 106) | 1.7 (1.1 – 2.6, 143) | 0.001 |
Bilirrubin (mg/dl) | 0.7 (0.5 – 1.1, 494) | 0.6 (0.4 – 0.8, 110) | 0.7 (0.4 – 1.1, 142) | 0.059 |
PaO2/FiO2 | 304.5 (212–364, 492) | 366 (315–407, 104) | 307.5 (238 – 387, 142) | 0.001 |
Suspected source of infection | 0.001 | |||
Respiratory | 120 (24%) | 16 (14%) | 43 (29%) | |
Urinary tract | 93 (18%) | 21 (19%) | 13 (9%) | |
Skin and soft tissues | 115 (23%) | 46 (41%) | 15 (10%) | |
Intra-abdominal | 54 (11%) | 15 (13%) | 24 (16%) | |
Undetermined | 66 (13%) | 3 (3%) | 25 (17%) | |
Others | 57 (11%) | 11 (10%) | 28 (19%) | |
No comorbidity | 220 (43%) | 55 (49%) | 63 (42%) | 0.513 |
Diabetes | 98 (19%) | 21 (19%) | 27 (18%) | 0.947 |
COPD | 63 (12%) | 4 (3%) | 27 (18%) | 0.002 |
CRF | 54 (11%) | 17 (15%) | 17 (11%) | 0.404 |
28-day mortality rate | 68 (13.5%) | 4 (3.6%) | 19 (13%) | 0.012 |