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Table 3 Haemodynamic variables and microcirculatory parameters for T0 and T30

From: Elevated central venous pressure is associated with impairment of microcirculatory blood flow in sepsis: a hypothesis generating post hoc analysis

 

T = 0 (n = 70 patients)

T = 30 (n = 70 patients)

P a

MAP (mmHg)

71 ± 12

68 ± 13

0.008*

Cardiac index (l/min/m 2 )

4.2 ± 1.3

4.1 ± 1.3

0.291

CVP (mmHg)

12.6 ± 4.8

11.9 ± 4.3

0.017*

Perfusion pressure (mmHg)

59 ± 13

56 ± 13

0.034*

PEEP (cm H 2 O)

13 ± 3

13 ± 3

0.425

SvO 2 (%)

71 ± 7.4

70 ± 8.4

0.141

Lactate (mmol/L)

2.6 ± 2.2

2.6 ± 2.3

0.779

Dopamine (n,%, μg/kg/min)

60, 86, 5.8 ± 3.7

61, 87, 5.9 ± 3.7

0.772

Norepinephrine (n,%, μg/kg/min)

33, 47, 0.07 ± 0.11

35, 50, 0.07 ± 0.15

0.401

MFI (AU)

1.58 ± 1.62

1.81 ± 0.92

0.027*

PPV (%)

91 ± 18

94 ± 12

0.197

TVD (mm/mm 2 )

14.27 ± 2.22

14.08 ± 2.01

0.415

PVD (mm/mm 2 )

14.11 ± 10.84

13.28 ± 2.71

0.496

  1. Mean ± SD unless specified otherwise. T0: directly after fulfillment of resuscitation endpoints. T30: 30 minutes after T0. CVP = Central venous pressure. MAP = mean arterial pressure. Perfusion pressure = MAP minus CVP. PEEP = positive end-expiratory pressure. SvO2 = mixed venous oxygen saturation. MFI = microvascular flow index. AU = arbitrary units. TVD = total vessel density. PPV = percentage of perfused vessels. PVD = perfused vessel density. TVD, MFI, PPV and PVD for small vessels, i.e. < 20 meter. aFor differences between T0 and T30. *P < 0.05 is considered statistically significant.
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BMC Anesthesiology

ISSN: 1471-2253

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