Does using a femoral nerve block for total knee replacement decrease postoperative delirium?

BMC Anesthesiology

Table 2 Intraoperative and postoperative data

	Femoral Block ± PCA		PCA only
	N1	Mean ± SD or N (%)	N2	Mean ± SD or N	P*
Anesthesia	31	14 (45%)	54	27 (50%)	0.67
General		14 (45%)		27 (50%)
Regional		17 (55%)		27 (50%)
Intraoperative fentanyl dose (mcg) ^†**	31	171.3 ± 160.8	53	259.9 ± 185.5	0.03
Length of hospital stay (days)	29	5.7 ± 6.4	52	5.0 ± 1.9	0.58
Altered sleep-wake cycle on POD1	30	10 (33%)	51	25 (49%)	0.17
Pain at rest on POD 1	31	4.6 ± 3.0	53	4.5 ± 2.9	0.89
Change in pain level, preop and POD1	31	0.9 ± 3.2	52	1.9 ± 3.7	0.20
Benzodiazepine use on POD 1	31	2 (6%)	54	9 (17%)	0.18
Hydromorphone dose on POD1(mg)**	31	4.3 ± 4.6	54	5.9 ± 6.1	0.24
Delirium on POD 1 or POD2	28	7 (25%)	51	31 (61%)	0.002

POD = postoperative day. Preop = preoperative. SD = standard deviation For a continuous variable, the numbers in parenthesis are the range of the variable
^†Intraoperative opioid: the amount of intravenous fentanyl administered intraoperatively
*For P-value, i) one-way ANOVA was used for the continuous variables; ii) Chi-square test was used for the categorical variables. If a cell count was less than 5, Fisher's exact test was used. **Wilcoxon non-parametric test was used

ISSN: 1471-2253