Variable | Group | BL | PE | 2 h | 4 h | 6 h | 8 h |
---|---|---|---|---|---|---|---|
PVPI | PROTV | 0.03 ± 0.01 | 0.02 ± 0.00 | 0.02 ± 0.00 | 0.02 ± 0.01 | 0.02 ± 0.01 | 0.02 ± 0.01†|
 | INJV | 0.04 ± 0.01 | 0.02 ± 0.01 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.04 ± 0.02 | 0.07 ± 0.03§ |
 | INJV + NI | 0.04 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.03 | 0.03 ± 0.03 | 0.04 ± 0.05§ | 0.06 ± 0.05§ |
PBVI (mL/m 2 ) | PROTV | 285 ± 127 | 196 ± 74 | 210 ± 75 | 215 ± 62 | 206 ± 69 | 210 ± 65 |
 | INJV | 229 ± 38 | 183 ± 49 | 179 ± 54 | 208 ± 31 | 181 ± 41 | 162 ± 47 |
 | INJV + NI | 208 ± 42 | 163 ± 55 | 171 ± 30 | 173 ± 25 | 181 ± 47 | 162 ± 38 |
GEDVI | PROTV | 602 ± 127 | 557 ± 175 | 537 ± 138 | 539 ± 144 | 567 ± 124 | 612 ± 144 |
(mL/m 2 ) | INJV | 603 ± 72 | 532 ± 70 | 527 ± 78 | 573 ± 65 | 598 ± 111§ | 622 ± 160§ |
 | INJV + NI | 615 ± 80 | 540 ± 48 | 594 ± 118 | 553 ± 66 | 617 ± 50§ | 590 ± 65§ |
CI | PROTV | 3.4 ± 0.8 | 3.9 ± 1.9 | 4.5 ± 1.7 | 4.4 ± 1.7 | 4.7 ± 1.4 | 4.6 ± 1.6 |
(L/min/m 2 ) | INJV | 3.6 ± 0.5 | 3.7 ± 0.7 | 4.4 ± 1.1 | 5.2 ± 1.2§ | 5.2 ± 1.3§ | 4.9 ± 1.7 |
 | INJV + NI | 4.1 ± 0.7 | 2.9 ± 0.5 | 3.8 ± 0.6§ | 3.7 ± 0.6§ | 3.9 ± 0.6§ | 3.5 ± 0.6 |
PAP (mm Hg) | PROTV | 12 ± 2 | 19 ± 5 | 20 ± 3 | 21 ± 4 | 20 ± 4 | 22 ± 7 |
 | INJV | 12 ± 3 | 18 ± 5 | 21 ± 4§ | 25 ± 5§ | 28 ± 6§,†| 31 ± 6§,†|
 | INJV + NI | 12 ± 2 | 17 ± 2 | 20 ± 4§ | 23 ± 7§ | 26 ± 6§ | 28 ± 6§ |
PAOP (mm Hg) | PROTV | 6 ± 3 | 6 ± 3 | 6 ± 3 | 9 ± 4§ | 9 ± 4§ | 8 ± 4§ |
 | INJV | 5 ± 2 | 8 ± 3 | 8 ± 3 | 12 ± 4§ | 14 ± 5§,†| 16 ± 4§,†,# |
 | INJV + NI | 6 ± 2 | 8 ± 3 | 10 ± 3§ | 9 ± 4 | 11 ± 4§ | 10 ± 3§ |
SVRI (dyn sec/cm -5 /m 2 ) | PROTV | 2096 ± 641 | 2757 ± 878 | 2001 ± 749§ | 2039 ± 923§ | 1851 ± 877§ | 1889 ± 872§ |
 | INJV | 2278 ± 418 | 2389 ± 572 | 2021 ± 592 | 1682 ± 491§ | 1547 ± 480§ | 1717 ± 514§ |
 | INJV + NI | 2034 ± 371 | 2743 ± 571 | 2352 ± 647 | 2198 ± 562 | 2299 ± 432 | 2332 ± 538 |
PVRI (dyn sec/cm -5 /m 2 ) | PROTV | 129 ± 53 | 286 ± 104 | 258 ± 123 | 247 ± 146 | 220 ± 81§ | 253 ± 136 |
 | INJV | 164 ± 73 | 231 ± 34 | 238 ± 54 | 212 ± 51 | 233 ± 78 | 276 ± 125 |
 | INJV + NI | 128 ± 56 | 266 ± 103 | 242 ± 72 | 299 ± 130 | 333 ± 155 | 426 ± 122‡ |