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Table 2 Time to recovery of the train-of-four ratio to 0.9, 0.8, and 0.7.

From: Reversal of profound vecuronium-induced neuromuscular block under sevoflurane anesthesia: sugammadex versus neostigmine

 

Sugammadex (n = 47)†

Neostigmine (n = 36)

Time to TOF ratio of 0.9, min

  

   Geometric mean

4.5*

66.2

   Median

3.3

49.9

   Interquartile range

2.3-6.6

46.0-96.6

   Range

1.4-68.4

46.0-312.7

Time to TOF ratio of 0.8, min

  

   Geometric mean

3.3*

58.9

   Median

2.7

43.9

   Interquartile range

1.8-4.4

42.9-79.8

   Range

1.2-65.2

35.3-250.9

Time to TOF ratio of 0.7, min

  

   Geometric mean

2.6*

48.8

   Median

2.5

36.4

   Interquartile range

1.6-3.3

34.9-67.5

   Range

1.1-61.9

27.5-192.2

  1. Recovery times were measured from the start of administration of sugammadex or neostigmine. Data are given for the intent-to-treat population, with imputed data.
  2. *p < 0.0001 versus neostigmine. †Data include the patient who received rocuronium plus neostigmine reversal rather than vecuronium plus sugammadex reversal in error, the times to a TOF ratio of 0.9 and 0.8 were not available. Her times to TOF 0.9 and 0.8 were imputed based on her time to TOF 0.7 of 61.9 minutes.TOF, train-of-four.
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BMC Anesthesiology

ISSN: 1471-2253

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