From: Effect of nitrous oxide on cisatracurium infusion demands: a randomized controlled trial
 | Patients | Controller performance | Time to 10% recovery of T1 following the initial bolus (min) | Cumulative dose of cisatracurium/IBW (mg/kg) | Steady-state rate of infusion of cisatracurium | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Group | No. (M/F) | ASA (1/2/3) | Age (yr) | Weight (kg) | Height (cm) | Offset from set-point (%) | SD from set-point (%) |  |  | Iss (mg/h) | Iss/IBW (mg·kg-1·h-1) |
Air/TIVA | 35 (20/15) | 23/12/0 | 47.3 ± 12.6 | 75.0 ± 14.3 | 173 ± 11 | 0.96 ± 1.25 | 3.03 ± 1.34 | 31.5 ± 6.1 | 12.4 ± 2.6 | 4.8 ± 1.5 | 0.072 ± 0.018 |
Nitrous oxide/TIVA | 35 (22/13) | 18/16/1 | 48.6 ± 12.3 | 77.7 ± 15.1 | 174 ± 10 | 1.10 ± 1.28 | 2.95 ± 1.19 | 34.4 ± 7.6 | 12.1 ± 2.2 | 4.5 ± 1.2 | 0.066 ± 0.017 |
Mean difference (95% CI) | Â | Â | 1.3 (-4.7, 7.2) | 2.7 (-4.3, 9.7) | 1.3 (-3.8, 6.3) | 0.14 (-0.47, 0.74) | -0.08 (-0.68, 0.53) | 2.9 (-0.4, 6.2) | 0.3 (-1.5, 0.8) | -0.3 (-1.0, 0.3) | -0.005 (-0.014, 0.003) |